5G3J

Discovery of New Selective Glucocorticoid Receptor Agonist Leads

Summary for 5G3J

• Entry DOI: 10.2210/pdb5g3j/pdb
• Descriptor: GLUCOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... (6 entities in total)
• Functional Keywords: dna binding protein, glucocorticoid receptor, nuclear hormone receptor, steroid receptor, signaling protein, ligand complex, peptide complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 35027.40

Authors

Berger, M.,Edman, K.,Wissler, L.,Neuhaus, R.,Rehwinkel, H.,Schacke, H.,Jaroch, S. (deposition date: 2016-04-27, release date: 2017-02-15, Last modification date: 2024-01-10)

• Primary citation: Berger, M.,Rehwinkel, H.,Schmees, N.,Schacke, H.,Edman, K.,Wissler, L.,Reichel, A.,Jaroch, S.; Discovery of New Selective Glucocorticoid Receptor Agonist Leads.; Bioorg.Med.Chem.Lett., 27:437-, 2017; PubMed: 28043796; DOI: 10.1016/J.BMCL.2016.12.047

Experimental method

X-RAY DIFFRACTION (2.4 Å)