1L8C

STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE

Summary for 1L8C

DescriptorCREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION (3 entities in total)
Functional Keywordsgene regulation
Biological sourceMus musculus (house mouse)
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Cellular locationCytoplasm (By similarity) P45481
Cytoplasm Q16665
Total number of polymer chains2
Total molecular weight16615.12
Authors
Dames, S.A.,Martinez-Yamout, M.,De Guzman, R.N.,Dyson, H.J.,Wright, P.E. (deposition date: 2002-03-19, release date: 2002-04-10, Last modification date: 2011-07-13)
Primary citation
Dames, S.A.,Martinez-Yamout, M.,De Guzman, R.N.,Dyson, H.J.,Wright, P.E.
Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
Proc.Natl.Acad.Sci.USA, 99:5271-5276, 2002
PubMed: 11959977 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.082121399
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers00.3%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report