1L8C
STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CREB-binding protein | polymer | 95 | 10853.7 | 1 | UniProt (P45481) Pfam (PF02135) In PDB | Mus musculus (house mouse) | |
| 2 | B | Hypoxia-inducible factor 1 alpha | polymer | 51 | 5565.2 | 1 | UniProt (Q16665) Pfam (PF08778) In PDB | Homo sapiens (human) | HIF-1 ALPHA, ARNT interacting protein, Member of PAS protein 1, MOP1 |
| 3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 1 - 95 (UniProt: P45481)
| PDB | External Database | Details |
|---|---|---|
| Gly 56 | Pro 400 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16418.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 16615.1 |
