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2N2H
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BU of 2n2h by Molmil
Solution structure of Sds3 in complex with Sin3A
分子名称: Paired amphipathic helix protein Sin3a, Sin3 histone deacetylase corepressor complex component SDS3
著者Clark, M, Radhakrishnan, I.
登録日2015-05-08
公開日2015-07-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
5YJO
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BU of 5yjo by Molmil
Crystal structure of SmyD3 in complex with covalent inhibitor 4
分子名称: Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ...
著者Baburajendran, N, Anna E, J.
登録日2017-10-11
公開日2018-10-17
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.135 Å)
主引用文献Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Acs Med.Chem.Lett., 10, 2019
8Q30
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BU of 8q30 by Molmil
Sulfolobus acidocaldarius AAP filament.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Isupov, M.N, Gaines, M, Daum, B, McLaren, M.
登録日2023-08-03
公開日2024-03-06
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献CryoEM reveals the structure of an archaeal pilus involved in twitching motility.
Nat Commun, 15, 2024
1WXL
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BU of 1wxl by Molmil
Solution Structure of the HMG-box domain in the SSRP1 subunit of FACT
分子名称: Single-strand recognition protein
著者Kasai, N, Tsunaka, Y, Ohki, I, Hirose, S, Morikawa, K, Tate, S.
登録日2005-01-26
公開日2005-08-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the HMG-box domain in the SSRP1 subunit of FACT
J.Biomol.Nmr, 32, 2005
7U3I
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BU of 7u3i by Molmil
GID4 in complex with compound 16
分子名称: 3-{[(5S)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]amino}phenol, GLYCEROL, Glucose-induced degradation protein 4 homolog
著者Chana, C.K, Sicheri, F.
登録日2022-02-27
公開日2022-10-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
7U3J
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BU of 7u3j by Molmil
GID4 in complex with compound 88
分子名称: (2S)-2-{[(2S)-2-({N-[(2,4-dimethoxyphenyl)methyl]glycyl}amino)-2-(thiophen-2-yl)acetyl]amino}-N-methyl-4-phenylbutanamide, GLYCEROL, Glucose-induced degradation protein 4 homolog
著者Chana, C.K, Sicheri, F.
登録日2022-02-27
公開日2022-10-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.642 Å)
主引用文献Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
1C9S
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BU of 1c9s by Molmil
CRYSTAL STRUCTURE OF A COMPLEX OF TRP RNA-BINDING ATTENUATION PROTEIN WITH A 53-BASE SINGLE STRANDED RNA CONTAINING ELEVEN GAG TRIPLETS SEPARATED BY AU DINUCLEOTIDES
分子名称: SINGLE STRANDED RNA (55-MER), TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN
著者Antson, A.A, Dodson, E.J, Dodson, G.G, Greaves, R.B, Chen, X.-P, Gollnick, P.
登録日1999-08-03
公開日1999-09-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA.
Nature, 401, 1999
6GQB
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BU of 6gqb by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y.
登録日2018-06-07
公開日2018-07-11
最終更新日2021-08-04
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
8C3T
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BU of 8c3t by Molmil
Structure of the GIsul2 transposon excisionase
分子名称: AlpA family phage regulatory protein
著者Smyshlyaev, G, Arinkin, V, Barabas, O.
登録日2022-12-28
公開日2024-01-10
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Cryo-EM structures of transposon end complexes explain antibiotic resistance transfer across diverse bacteria
To Be Published
1C4Z
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BU of 1c4z by Molmil
STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY
分子名称: UBIQUITIN CONJUGATING ENZYME E2, UBIQUITIN-PROTEIN LIGASE E3A
著者Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P.
登録日1999-10-14
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
2JM1
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BU of 2jm1 by Molmil
Structures and chemical shift assignments for the ADD domain of the ATRX protein
分子名称: Transcriptional regulator ATRX, ZINC ION
著者Yang, J, Neuhaus, D.
登録日2006-09-13
公開日2007-06-26
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc.Natl.Acad.Sci.USA, 104, 2007
8JQ1
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BU of 8jq1 by Molmil
Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1)
分子名称: Insulinoma-associated protein 1, ZINC ION
著者He, X.L, Yang, Y.H.
登録日2023-06-13
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of zinc fingers 1-2 (fragment 257-320) from human insulinoma-associated protein 1(INSM1)
To Be Published
8JXK
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BU of 8jxk by Molmil
Crystal Structure of Rv0047c from Mycobacterium tuberculosis
分子名称: Conserved protein
著者Ansari, M.S, Yadav, V, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A.
登録日2023-06-30
公開日2024-07-03
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal Structure of Rv0047c from Mycobacterium tuberculosis
To Be Published
5Y6P
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BU of 5y6p by Molmil
Structure of the phycobilisome from the red alga Griffithsia pacifica
分子名称: ApcD, ApcF, LC, ...
著者Zhang, J, Ma, J.F, Liu, D.S, Sun, S, Sui, S.F.
登録日2017-08-13
公開日2017-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of phycobilisome from the red alga Griffithsia pacifica
Nature, 551, 2017
5KZ0
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BU of 5kz0 by Molmil
Structure of Human Anaplastic Lymphoma Kinase in Complex With 2-[(1R)-1-{[2-amino-5-(1,3-dimethyl-1H-pyrazol-4-yl)pyridin-3-yl]oxy}ethyl]-4-fluoro-N,N-dimethylbenzamide
分子名称: 2-[(1~{R})-1-[2-azanyl-5-(1,3-dimethylpyrazol-4-yl)pyridin-3-yl]oxyethyl]-4-fluoranyl-~{N},~{N}-dimethyl-benzamide, ALK tyrosine kinase receptor
著者McTigue, M, Deng, Y.L, Liu, W, Brooun, A.
登録日2016-07-22
公開日2016-08-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations.
J. Med. Chem., 57, 2014
1UTD
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BU of 1utd by Molmil
The structure of the trp RNA-binding attenuation protein (TRAP) bound to a 63-nucleotide RNA molecule containing GAGUUU repeats
分子名称: 5'-R(*GP*UP*UP*UP*GP*AP)-3', TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN
著者Hopcroft, N.H, Manfredo, A, Wendt, A.L, Brzozowski, A.M, Gollnick, P, Antson, A.A.
登録日2003-12-08
公開日2004-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Interaction of RNA with Trap: The Role of Triplet Repeats and Separating Spacer Nucleotides
J.Mol.Biol., 338, 2004
1RBT
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BU of 1rbt by Molmil
STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Kanaya, S, Morikawa, K, Nakamura, H.
登録日1993-02-16
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of mutants of Escherichia coli ribonuclease HI with enhanced thermostability.
Protein Eng., 6, 1993
8RYK
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BU of 8ryk by Molmil
IL-1beta in complex with macrocyclic peptide hit
分子名称: Interleukin-1 beta, Macrocyclic peptide
著者Rondeau, J.-M, Lehmann, S.
登録日2024-02-09
公開日2024-05-22
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches.
J.Med.Chem., 67, 2024
1VC1
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BU of 1vc1 by Molmil
Crystal structure of the TM1442 protein from Thermotoga maritima, a homolog of the Bacillus subtilis general stress response anti-anti-sigma factor RsbV
分子名称: Putative anti-sigma factor antagonist TM1442
著者Lee, J.Y, Ahn, H.J, Ha, K.S, Suh, S.W.
登録日2004-03-03
公開日2004-09-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the TM1442 protein from Thermotoga maritima, a homolog of the Bacillus subtilis general stress response anti-anti-sigma factor RsbV
Proteins, 56, 2004
8CKB
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BU of 8ckb by Molmil
Asymmetric reconstruction of the crAss001 virion
分子名称: Auxiliary capsid protein gp36, Cargo protein 1 gp45, Head fiber dimer protein gp29, ...
著者Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A.
登録日2023-02-16
公開日2023-11-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.39 Å)
主引用文献Structural atlas of the most abundant human gut virus
Nature
8OTZ
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BU of 8otz by Molmil
48-nm repeat of the native axonemal doublet microtubule from bovine sperm
分子名称: ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ...
著者Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T.
登録日2023-04-21
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural specializations of the sperm tail.
Cell, 186, 2023
8HLW
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BU of 8hlw by Molmil
Crystal structure of SIRT3 in complex with H4K16la peptide
分子名称: (2S)-2-HYDROXYPROPANOIC ACID, Histone H4 residues 20-27, NAD-dependent protein deacetylase sirtuin-3, ...
著者Zhuming, F, Hao, Q.
登録日2022-12-01
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of SIRT3 as an eraser of H4K16la.
Iscience, 26, 2023
6I7O
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BU of 6i7o by Molmil
The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Cheng, J, Becker, T, Beckmann, R.
登録日2018-11-16
公開日2019-01-16
最終更新日2019-03-13
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
5JH5
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Structural Basis for the Hierarchical Assembly of the Core of PRC1.1
分子名称: BCL-6 corepressor-like protein 1, Lysine-specific demethylase 2B, Polycomb group RING finger protein 1, ...
著者Wong, S.J, Taylor, A.B, Hart, P.J, Kim, C.A.
登録日2016-04-20
公開日2016-09-14
最終更新日2016-10-19
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.
Structure, 24, 2016
5Y0H
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Solution structure of arenicin-3 derivative N6
分子名称: N6
著者Liu, X.H, Wang, J.H.
登録日2017-07-17
公開日2017-07-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis
Sci Rep, 7, 2017

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