8RYK
IL-1beta in complex with macrocyclic peptide hit
Summary for 8RYK
| Entry DOI | 10.2210/pdb8ryk/pdb |
| Descriptor | Interleukin-1 beta, Macrocyclic peptide (3 entities in total) |
| Functional Keywords | peptide discovery platform, cytokine |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 39012.20 |
| Authors | Rondeau, J.-M.,Lehmann, S. (deposition date: 2024-02-09, release date: 2024-05-22, Last modification date: 2024-06-05) |
| Primary citation | Vulpetti, A.,Rondeau, J.M.,Bellance, M.H.,Blank, J.,Boesch, R.,Boettcher, A.,Bornancin, F.,Buhr, S.,Connor, L.E.,Dumelin, C.E.,Esser, O.,Hediger, M.,Hintermann, S.,Hommel, U.,Koch, E.,Lapointe, G.,Leder, L.,Lehmann, S.,Lehr, P.,Meier, P.,Muller, L.,Ostermeier, D.,Ramage, P.,Schiebel-Haddad, S.,Smith, A.B.,Stojanovic, A.,Velcicky, J.,Yamamoto, R.,Hurth, K. Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67:8141-8160, 2024 Cited by PubMed: 38728572DOI: 10.1021/acs.jmedchem.4c00240 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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