8RYK
IL-1beta in complex with macrocyclic peptide hit
Functional Information from PROSITE/UniProt
| site_id | PS00253 |
| Number of Residues | 21 |
| Details | INTERLEUKIN_1 Interleukin-1 signature. FeSAqfPnwYISTsqaenmpV |
| Chain | Residue | Details |
| A | PHE112-VAL132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Involved in receptor binding |
| Chain | Residue | Details |
| A | ARG4 | |
| B | ARG4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | SITE: Important for interaction with integrin => ECO:0000269|PubMed:29030430 |
| Chain | Residue | Details |
| A | LYS55 | |
| B | LYS88 | |
| A | LYS63 | |
| A | LYS65 | |
| A | LYS74 | |
| A | LYS88 | |
| B | LYS55 | |
| B | LYS63 | |
| B | LYS65 | |
| B | LYS74 |
