8TVA
 
 | | Outer Mat-T4P complex | | 分子名称: | Fimbrial protein, Maturation protein | | 著者 | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | | 登録日 | 2023-08-17 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (8.55 Å) | | 主引用文献 | Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
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8TV9
 | | Inner Mat-T4P complex | | 分子名称: | Fimbrial protein, Maturation protein | | 著者 | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | | 登録日 | 2023-08-17 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (8.15 Å) | | 主引用文献 | Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
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8TV8
 | | Crystal structure of nontypeable Haemophilus influenzae SapA | | 分子名称: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance | | 著者 | Tanaka, K.J, Buechel, E.R, Rivera, K.G, Pinkett, H.W. | | 登録日 | 2023-08-17 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Antimicrobial Peptide Recognition Motif of the Substrate Binding Protein SapA from Nontypeable Haemophilus influenzae .
Biochemistry, 63, 2024
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8TV7
 | | SARS-CoV-2 Mac1 in complex with MDOLL-0229 | | 分子名称: | (1R,2R)-2-{[3-(methoxycarbonyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, GLYCEROL, Papain-like protease nsp3 | | 著者 | Wazir, S, Maksimainen, M, Lehtio, L. | | 登録日 | 2023-08-17 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target.
J.Med.Chem., 67, 2024
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8TV6
 | | SARS-CoV-2 Mac1 in complex with MDOLL-0169 | | 分子名称: | (1R,6R)-6-{[3-(methoxycarbonyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]carbamoyl}cyclohex-3-ene-1-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Wazir, S, Maksimainen, M, Lehtio, L. | | 登録日 | 2023-08-17 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target.
J.Med.Chem., 67, 2024
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8TV4
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8TV1
 | | Structure of the EphA2 LBDCRD bound to FabS1C_L1 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Ephrin type-A receptor 2, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-08-17 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation
To be published
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8TV0
 | | XptA2 wild type | | 分子名称: | XptA2 | | 著者 | Martin, C.L, Aller, S.G. | | 登録日 | 2023-08-17 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains.
Int J Mol Sci, 24, 2023
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8TUX
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8TUW
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8TUV
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8TUU
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8TUT
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8TUS
 | | WU Polyomavirus LTA NLS bound to importin alpha 2 | | 分子名称: | Importin subunit alpha-1, Large T antigen | | 著者 | Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. | | 登録日 | 2023-08-17 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8TUR
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8TUQ
 | | STL Polyomavirus LTA NLS bound to importin alpha 2 | | 分子名称: | Importin subunit alpha-1, Large T antigen | | 著者 | Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. | | 登録日 | 2023-08-17 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8TUP
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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8TUN
 | | S. thermodepolymerans KpsM-KpsE in Glycolipid 1 state with rigid body fitted KpsT | | 分子名称: | (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ... | | 著者 | Kuklewicz, J, Zimmer, J. | | 登録日 | 2023-08-16 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
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8TUM
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8TUL
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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8TUK
 | | Alvinella ASCC1 KH and Phosphodiesterase/Ligase Domain | | 分子名称: | 1,2-ETHANEDIOL, Activating signal cointegrator 1 complex subunit 1, IMIDAZOLE | | 著者 | Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Chinnam, N.B. | | 登録日 | 2023-08-16 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase.
J.Biol.Chem., 300, 2024
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8TUI
 | | Crystal structure of Fab-Lirilumab bound to KIR2DL3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ... | | 著者 | Lorig-Roach, N, DuBois, R.M. | | 登録日 | 2023-08-16 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
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8TUH
 | | HLA B7:02 with RPIIRPATL | | 分子名称: | 1,2-ETHANEDIOL, ARG-PRO-ILE-ILE-ARG-PRO-ALA-THR-LEU, Beta-2-microglobulin, ... | | 著者 | Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J. | | 登録日 | 2023-08-16 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.200106 Å) | | 主引用文献 | CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.
Nat Commun, 15, 2024
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8TUG
 | | Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) | | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-16 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TUD
 | | IgG1 Fc Heterodimer combYSelect2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | | 著者 | Azzam, T, Du, J.J, Sundberg, E.J. | | 登録日 | 2023-08-16 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.
Sci Adv, 10, 2024
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