8TUK

Alvinella ASCC1 KH and Phosphodiesterase/Ligase Domain

Summary for 8TUK

Entry DOI	10.2210/pdb8tuk/pdb
Related	8TLY
Descriptor	Activating signal cointegrator 1 complex subunit 1, IMIDAZOLE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	alkylation response, rna damage, kh domain, phosphoesterase domain, rna ligase domain, rna binding protein
Biological source	Alvinella pompejana
Total number of polymer chains	1
Total formula weight	37067.85
Authors	Tsutakawa, S.E.,Tainer, J.A.,Arvai, A.S.,Chinnam, N.B. (deposition date: 2023-08-16, release date: 2024-07-10)
Primary citation	Chinnam, N.B.,Thapar, R.,Arvai, A.S.,Sarker, A.H.,Soll, J.M.,Paul, T.,Syed, A.,Rosenberg, D.J.,Hammel, M.,Bacolla, A.,Katsonis, P.,Asthana, A.,Tsai, M.S.,Ivanov, I.,Lichtarge, O.,Silverman, R.H.,Mosammaparast, N.,Tsutakawa, S.E.,Tainer, J.A. ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase. J.Biol.Chem., 300:107368-107368, 2024 Cited by PubMed: 38750793 DOI: 10.1016/j.jbc.2024.107368 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation