8TUP

Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition

Summary for 8TUP

• Entry DOI: 10.2210/pdb8tup/pdb
• Related: 8TUL
• EMDB information: 41624 41628
• Descriptor: Magnesium transporter MRS2 homolog, mitochondrial, MAGNESIUM ION (3 entities in total)
• Functional Keywords: magnesium, ion channel, membrane protein, metal transport, ion translocation, divalent ion, pentamer
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 256940.50

Authors

Lai, L.T.F.,Balaraman, J.,Zhou, F.,Matthies, D. (deposition date: 2023-08-16, release date: 2023-09-13, Last modification date: 2023-11-15)

• Primary citation: Lai, L.T.F.,Balaraman, J.,Zhou, F.,Matthies, D.; Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms; Nat Commun, 14:7207-, 2023; DOI: 10.1038/s41467-023-42599-3

Experimental method

ELECTRON MICROSCOPY (3.3 Å)