8TUP
Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Magnesium transporter MRS2 homolog, mitochondrial | polymer | 451 | 51373.5 | 5 | UniProt (Q9HD23) Pfam (PF22099) | Homo sapiens (human) | |
| 2 | F, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | I, J, K, L, M (A, B, C, D, E) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 443 (UniProt: Q9HD23)
| PDB | External Database | Details |
|---|---|---|
| Asp 444 | - | expression tag |
| Tyr 445 | - | expression tag |
| Lys 446 | - | expression tag |
| Asp 447 | - | expression tag |
| Asp 448 | - | expression tag |
| Asp 449 | - | expression tag |
| Asp 450 | - | expression tag |
| Lys 451 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 256867.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 72.9 | |
| All* | Total formula weight | 256940.5 |
