2Z35
| Crystal structure of immune receptor | 分子名称: | T-cell receptor alpha-chain, T-cell receptor beta-chain | 著者 | Feng, D, Bond, C.J, Ely, L.K, Garcia, K.C. | 登録日 | 2007-06-01 | 公開日 | 2007-10-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon' Nat.Immunol., 8, 2007
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3CDC
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3CDY
| AL-09 H87Y, immunoglobulin light chain variable domain | 分子名称: | IMMUNOGLOBULIN LIGHT CHAIN | 著者 | Baden, E.M, Randles, E.G, Aboagye, A.K, Thompson, J.R, Ramirez-Alvarado, M. | 登録日 | 2008-02-27 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural insights into the role of mutations in amyloidogenesis. J.Biol.Chem., 283, 2008
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3CDF
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6U6V
| Crystal structure of human PD-1H / VISTA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation | 著者 | Slater, B.T, Han, X, Chen, L, Xiong, Y. | 登録日 | 2019-08-30 | 公開日 | 2020-01-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insight into T cell coinhibition by PD-1H (VISTA). Proc.Natl.Acad.Sci.USA, 117, 2020
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1A6W
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1A7N
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1A7B
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6TXZ
| FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | 分子名称: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | 著者 | Musil, D, Sood, V. | 登録日 | 2020-01-15 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
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6UMV
| Human apo PD-1 double mutant | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | 著者 | Tang, S, Kim, P.S. | 登録日 | 2019-10-10 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.424 Å) | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery. Proc.Natl.Acad.Sci.USA, 116, 2019
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1BFV
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1AR2
| DISULFIDE-FREE IMMUNOGLOBULIN FRAGMENT | 分子名称: | REI | 著者 | Uson, I, Bes, M.T, Sheldrick, G.M, Schneider, T.R, Hartsch, T, Fritz, H.-J. | 登録日 | 1997-08-08 | 公開日 | 1997-11-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray crystallography reveals stringent conservation of protein fold after removal of the only disulfide bridge from a stabilized immunoglobulin variable domain. Structure Fold.Des., 2, 1997
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1BWW
| BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT | 分子名称: | PROTEIN (IG KAPPA CHAIN V-I REGION REI) | 著者 | Uson, I, Pohl, E, Schneider, T.R, Dauter, Z, Schmidt, A, Fritz, H.J, Sheldrick, G.M. | 登録日 | 1998-09-29 | 公開日 | 1998-10-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints. Acta Crystallogr.,Sect.D, 55, 1999
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1A7R
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6VQN
| Co-crystal structure of human PD-L1 complexed with Compound A | 分子名称: | N,N'-(2,2'-dimethyl[1,1'-biphenyl]-3,3'-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide), Programmed cell death 1 ligand 1 | 著者 | White, A, Lakshminarasimhan, D, Leo, C, Suto, R.K. | 登録日 | 2020-02-05 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun, 12, 2021
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6VSV
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1A6V
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1B0W
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6VRR
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6UMT
| High-affinity human PD-1 PD-L2 complex | 分子名称: | MAGNESIUM ION, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | 著者 | Tang, S, Kim, P.S. | 登録日 | 2019-10-10 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery. Proc.Natl.Acad.Sci.USA, 116, 2019
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6UMU
| Human apo PD-1 triple mutant | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | 著者 | Tang, S, Kim, P.S. | 登録日 | 2019-10-10 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.183 Å) | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery. Proc.Natl.Acad.Sci.USA, 116, 2019
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1BWM
| A SINGLE-CHAIN T CELL RECEPTOR | 分子名称: | PROTEIN (ALPHA-BETA T CELL RECEPTOR (TCR) (D10)) | 著者 | Hare, B.J, Wyss, D.F, Reinherz, E.L, Wagner, G. | 登録日 | 1998-09-23 | 公開日 | 1999-07-22 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor. Nat.Struct.Biol., 6, 1999
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1A64
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1A6P
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1CD0
| STRUCTURE OF HUMAN LAMDA-6 LIGHT CHAIN DIMER JTO | 分子名称: | PROTEIN (JTO, A VARIABLE DOMAIN FROM LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN) | 著者 | Pokkuluri, P.R, Solomon, A, Weiss, D.T, Stevens, F.J, Schiffer, M. | 登録日 | 1999-03-05 | 公開日 | 2000-03-06 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tertiary structure of human lambda 6 light chains. Amyloid, 6, 1999
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