Human apo PD-1 triple mutant

Summary for 6UMU

DescriptorProgrammed cell death protein 1, CHLORIDE ION (3 entities in total)
Functional Keywordspd-1, immune checkpoint, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight14584.11
Tang, S.,Kim, P.S. (deposition date: 2019-10-10, release date: 2019-11-27, Last modification date: 2019-12-18)
Primary citation
Tang, S.,Kim, P.S.
A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116:24500-24506, 2019
PubMed: 31727844 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1916916116
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.166100 3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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