6UMU
Human apo PD-1 triple mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death protein 1 | polymer | 129 | 14513.2 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 2 | B, C (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 33 - 150 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Met 32 | - | initiating methionine |
| Gly 74 | Asn 74 | engineered mutation |
| Pro 76 | Thr 76 | engineered mutation |
| Ser 93 | Cys 93 | conflict |
| Val 132 | Ala 132 | engineered mutation |
| Gly 151 | - | expression tag |
| Ser 152 | - | expression tag |
| Trp 153 | - | expression tag |
| Ser 154 | - | expression tag |
| His 155 | - | expression tag |
| Pro 156 | - | expression tag |
| Gln 157 | - | expression tag |
| Phe 158 | - | expression tag |
| Glu 159 | - | expression tag |
| Lys 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14513.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 14584.1 |
