6UMT

High-affinity human PD-1 PD-L2 complex

Summary for 6UMT

• Entry DOI: 10.2210/pdb6umt/pdb
• Descriptor: Programmed cell death protein 1, Programmed cell death 1 ligand 2, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: pd-1, pd-l2, immune checkpoint, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 29402.68

Authors

Tang, S.,Kim, P.S. (deposition date: 2019-10-10, release date: 2019-11-27, Last modification date: 2023-10-11)

• Primary citation: Tang, S.,Kim, P.S.; A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.; Proc.Natl.Acad.Sci.USA, 116:24500-24506, 2019; PubMed: 31727844; DOI: 10.1073/pnas.1916916116

Experimental method

X-RAY DIFFRACTION (1.986 Å)