6UMT
High-affinity human PD-1 PD-L2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Programmed cell death protein 1 | polymer | 140 | 15429.4 | 1 | UniProt (Q15116) Pfam (PF07686) In PDB | Homo sapiens (Human) | hPD-1 |
2 | B | Programmed cell death 1 ligand 2 | polymer | 123 | 13949.0 | 1 | UniProt (Q9BQ51) In PDB | Homo sapiens (Human) | Programmed death ligand 2,Butyrophilin B7-DC,B7-DC |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 33 - 150 (UniProt: Q15116)
B: 1 - 123 (UniProt: Q9BQ51)
PDB | External Database | Details |
---|---|---|
Met 14 | - | expression tag |
Gly 15 | - | expression tag |
Trp 16 | - | expression tag |
Ser 17 | - | expression tag |
Cys 18 | - | expression tag |
Ile 19 | - | expression tag |
Ile 20 | - | expression tag |
Leu 21 | - | expression tag |
Phe 22 | - | expression tag |
Leu 23 | - | expression tag |
Val 24 | - | expression tag |
Ala 25 | - | expression tag |
Thr 26 | - | expression tag |
Ala 27 | - | expression tag |
Thr 28 | - | expression tag |
Gly 29 | - | expression tag |
Val 30 | - | expression tag |
His 31 | - | expression tag |
Ser 32 | - | expression tag |
Ser 49 | Asn 49 | conflict |
Ser 58 | Asn 58 | conflict |
Gly 74 | Asn 74 | engineered mutation |
Pro 76 | Thr 76 | engineered mutation |
Ser 93 | Cys 93 | conflict |
Asp 116 | Asn 116 | conflict |
Val 132 | Ala 132 | engineered mutation |
Pro 151 | - | expression tag |
Glu 152 | - | expression tag |
Ala 153 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp 37 | Asn 37 | conflict |
Asp 64 | Asn 64 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 29378.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 24.3 | |
All* | Total formula weight | 29402.7 |