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6V2K
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BU of 6v2k by Molmil
The nucleosome structure after H2A-H2B exchange
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
著者Arimura, Y, Hirano, R, Kurumizaka, H.
登録日2019-11-24
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome.
Commun Biol, 4, 2021
6UGM
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BU of 6ugm by Molmil
Structural basis of COMPASS eCM recognition of an unmodified nucleosome
分子名称: Bre2, DNA (146-MER), H3 N-terminus, ...
著者Hsu, P.L, Shi, H, Zheng, N.
登録日2019-09-26
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
6W4L
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BU of 6w4l by Molmil
The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis
分子名称: Histone H2B 1.1,Histone H2A type 1, PYROPHOSPHATE
著者Warren, C, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2020-03-11
公開日2020-05-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structure of a single-chain H2A/H2B dimer.
Acta Crystallogr.,Sect.F, 76, 2020
6VYP
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BU of 6vyp by Molmil
Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate
分子名称: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ...
著者Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T.
登録日2020-02-27
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Mol.Cell, 78, 2020
6W5I
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BU of 6w5i by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01)
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6W5N
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BU of 6w5n by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6W5M
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BU of 6w5m by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6WKR
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BU of 6wkr by Molmil
PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome
分子名称: DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R.
登録日2020-04-16
公開日2021-02-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Science, 371, 2021
5WCU
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BU of 5wcu by Molmil
Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5
分子名称: DNA (167-MER), Histone H2A, Histone H2B, ...
著者Jiang, J.S, Zhou, B.R.
登録日2017-07-02
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.53 Å)
主引用文献Revisit of Reconstituted 30-nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures.
J. Mol. Biol., 430, 2018
5X0X
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BU of 5x0x by Molmil
Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome
分子名称: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
著者Li, M, Liu, X, Xia, X, Chen, Z, Li, X.
登録日2017-01-23
公開日2017-04-19
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
5X0Y
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BU of 5x0y by Molmil
Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome
分子名称: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
著者Li, M, Liu, X, Xia, X, Chen, Z, Li, X.
登録日2017-01-23
公開日2017-04-19
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.69 Å)
主引用文献Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
5XF3
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BU of 5xf3 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XM0
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BU of 5xm0 by Molmil
The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4
分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
著者Taguchi, H, Horikoshi, N, Kurumizaka, H.
登録日2017-05-12
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.874 Å)
主引用文献Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
5XF5
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BU of 5xf5 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration)
分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF6
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BU of 5xf6 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker
分子名称: DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5XF4
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BU of 5xf4 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration)
分子名称: (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5X7X
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BU of 5x7x by Molmil
The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Taguchi, H, Kurumizaka, H.
登録日2017-02-27
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.184 Å)
主引用文献Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
5XM1
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BU of 5xm1 by Molmil
The mouse nucleosome structure containing H2A, H2B type3-A, H3mm7, and H4
分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
著者Taguchi, H, Horikoshi, N, Kurumizaka, H.
登録日2017-05-12
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
5Y0C
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BU of 5y0c by Molmil
Crystal Structure of the human nucleosome at 2.09 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5Y0D
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BU of 5y0d by Molmil
Crystal Structure of the human nucleosome containing the H2B E76K mutant
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5ZBA
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BU of 5zba by Molmil
Crystal structure of Rtt109-Asf1-H3-H4-CoA complex
分子名称: COENZYME A, DNA damage response protein Rtt109, putative, ...
著者Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
登録日2018-02-10
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5Z23
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BU of 5z23 by Molmil
Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Arimura, Y, Tachiwana, H, Takagi, H.
登録日2017-12-28
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
5Z3L
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BU of 5z3l by Molmil
Structure of Snf2-nucleosome complex in apo state
分子名称: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
著者Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
登録日2018-01-08
公開日2019-04-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5ZBX
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BU of 5zbx by Molmil
The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D)
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Takagi, H, Kurumizaka, H.
登録日2018-02-13
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
5ZBB
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BU of 5zbb by Molmil
Crystal structure of Rtt109-Asf1-H3-H4 complex
分子名称: DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ...
著者Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
登録日2018-02-10
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018

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