1UYU
| Xenon COMPLEX OF wildtype P450CAM FROM PSEUDOMONAS PUTIDA | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, POTASSIUM ION, ... | 著者 | Wade, R.C, Winn, P.J, Schlichting, I, Sudarko, X. | 登録日 | 2004-03-02 | 公開日 | 2005-03-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Survey of Active Site Access Channels in Cytochromes P450 J.Inorg.Biochem., 98, 2004
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2P85
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2H7R
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2PG5
| Crystal Structure of Human Microsomal P450 2A6 N297Q | 分子名称: | 1,2-ETHANEDIOL, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. | 登録日 | 2007-04-06 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464, 2007
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2PG7
| Crystal Structure of Human Microsomal P450 2A6 N297Q/I300V | 分子名称: | Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. | 登録日 | 2007-04-06 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464, 2007
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2H7S
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1T85
| Crystal Structure of the Ferrous CO-bound Cytochrome P450cam Mutant (L358P/C334A) | 分子名称: | CAMPHOR, CARBON MONOXIDE, Cytochrome P450-cam, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T86
| Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A) | 分子名称: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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2Q9F
| Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate | 分子名称: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Cytochrome P450 46A1, GLYCEROL, ... | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | 登録日 | 2007-06-12 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2PG6
| Crystal Structure of Human Microsomal P450 2A6 L240C/N297Q | 分子名称: | Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. | 登録日 | 2007-04-06 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464, 2007
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2HI4
| Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone | 分子名称: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1A2, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sansen, S, Yano, J.K, Reynald, R.L, Schoch, G.S, Stout, C.D, Johnson, E.F. | 登録日 | 2006-06-29 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2. J.Biol.Chem., 282, 2007
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1W0E
| Crystal structure of human cytochrome P450 3A4 | 分子名称: | CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H. | 登録日 | 2004-06-03 | 公開日 | 2004-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone Science, 305, 2004
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2H7Q
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2Q6N
| Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole | 分子名称: | 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Zhao, Y, Sun, L, Muralidhara, B.K, Kumar, S, White, M.A, Stout, C.D, Halpert, J.R. | 登録日 | 2007-06-05 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4. Biochemistry, 46, 2007
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1SE6
| Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ... | 著者 | Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R. | 登録日 | 2004-02-16 | 公開日 | 2005-01-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2. J.Biol.Chem., 280, 2005
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1SMI
| A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme | 分子名称: | Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D. | 登録日 | 2004-03-09 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme J.Biol.Chem., 279, 2004
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1SMJ
| Structure of the A264E mutant of cytochrome P450 BM3 complexed with palmitoleate | 分子名称: | Bifunctional P-450:NADPH-P450 reductase, PALMITOLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D. | 登録日 | 2004-03-09 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme J.Biol.Chem., 279, 2004
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2NNJ
| CYP2C8dH complexed with felodipine | 分子名称: | Cytochrome P450 2C8, FELODIPINE, PALMITIC ACID, ... | 著者 | Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2006-10-24 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J.Biol.Chem., 283, 2008
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1T87
| Crystal Structure of the Ferrous CO-bound Cytochrome P450cam (C334A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CARBON MONOXIDE, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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2IAG
| Crystal structure of human prostacyclin synthase | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, SODIUM ION | 著者 | Chiang, C.-W, Yeh, H.-C, Wang, L.-H, Chan, N.-L. | 登録日 | 2006-09-08 | 公開日 | 2006-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of the Human Prostacyclin Synthase J.Mol.Biol., 364, 2006
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1T88
| Crystal Structure of the Ferrous Cytochrome P450cam (C334A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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2NNI
| CYP2C8dH complexed with montelukast | 分子名称: | Cytochrome P450 2C8, MONTELUKAST, PALMITIC ACID, ... | 著者 | Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2006-10-24 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J.Biol.Chem., 283, 2008
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2NNH
| CYP2C8dH complexed with 2 molecules of 9-cis retinoic acid | 分子名称: | (9cis)-retinoic acid, Cytochrome P450 2C8, PALMITIC ACID, ... | 著者 | Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2006-10-24 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J.Biol.Chem., 283, 2008
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2Q9G
| Crystal structure of human cytochrome P450 46A1 | 分子名称: | Cytochrome P450 46A1, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | 登録日 | 2007-06-12 | 公開日 | 2008-06-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2QBO
| Crystal structure of the P450cam G248V mutant in the cyanide bound state | 分子名称: | CAMPHOR, CYANIDE ION, Cytochrome P450-cam, ... | 著者 | von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. | 登録日 | 2007-06-18 | 公開日 | 2007-12-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
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