2JJO

Structure of cytochrome P450 EryK in complex with its natural substrate erD

Summary for 2JJO

Entry DOI	10.2210/pdb2jjo/pdb
Related	2JJN 2JJP 2VRU 2VRV 2WIO
Descriptor	CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin D, ... (4 entities in total)
Functional Keywords	iron, heme, monooxygenase, metal-binding, antibiotic biosynthesis, tie-rod mechanism of action, oxidoreductase, substrate specificity
Biological source	SACCHAROPOLYSPORA ERYTHRAEA
Total number of polymer chains	1
Total formula weight	46667.42
Authors	Savino, C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Vallone, B. (deposition date: 2008-04-15, release date: 2009-07-14, Last modification date: 2023-12-13)
Primary citation	Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Jemth, P.,Gianni, S.,Vallone, B. Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284:29170-, 2009 Cited by PubMed: 19625248 DOI: 10.1074/JBC.M109.003590 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation