8TWU

Crystal structure of Cytochrome P450 AspB bound to N1-methylated cyclo-L-Trp-L-Pro

Summary for 8TWU

Entry DOI	10.2210/pdb8twu/pdb
Descriptor	Cytochrome P450 AspB, PROTOPORPHYRIN IX CONTAINING FE, (3S,5S,8aS)-3-[(1-methyl-1H-indol-3-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, ... (5 entities in total)
Functional Keywords	dimerase, oxidoreductase
Biological source	Streptomyces
Total number of polymer chains	1
Total formula weight	45835.94
Authors	Gering, H.E.,Li, X.,Tang, H.,Swartz, P.D.,Chang, W.-C.,Makris, T.M. (deposition date: 2023-08-21, release date: 2023-09-20)
Primary citation	Gering, H.E.,Li, X.,Tang, H.,Swartz, P.D.,Chang, W.C.,Makris, T.M. A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. J.Am.Chem.Soc., 145:19256-19264, 2023 Cited by PubMed: 37611404 DOI: 10.1021/jacs.3c04542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation