PDB: 37224 件ウェブページステータス検索Chemie searchBIRD

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8E6J	3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1) 分子名称: 3H03 fragment antigen binding heavy chain, 3H03 fragment antigen binding light chain, Neuraminidase 著者 Turner, H.L, Ozorowski, G, Ward, A.B. 登録日 2022-08-22 公開日 2023-08-09 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
8E0B	Crystal structure of human Sar1bT39N 分子名称: GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Sar1bT39N 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.212 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
6YO1	Crystal structure of ribonuclease A solved by vanadium SAD phasing 分子名称: Ribonuclease pancreatic, URIDINE-2',3'-VANADATE 著者 El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A. 登録日 2020-04-14 公開日 2020-11-04 最終更新日 2020-12-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Experimental phasing with vanadium and application to nucleotide-binding membrane proteins. Iucrj, 7, 2020
8E0C	Crystal structure of human Sar1bH79G 分子名称: GTP-binding protein SAR1b, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.993 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
6MBT	Crystal structure of wild-type KRAS bound to GDP and Mg (Space group C2) 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Dharmaiah, S, Tran, T.H, Yan, W, Simanshu, D.K. 登録日 2018-08-30 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structures of N-terminally processed KRAS provide insight into the role of N-acetylation. Sci Rep, 9, 2019
5XIR	Solution structure for human HSP70 substrate binding domain L542Y mutant 分子名称: Heat shock 70 kDa protein 1A 著者 Hoshikawa, M, Tochio, N, Tate, S. 登録日 2017-04-27 公開日 2018-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication. Molecules, 23, 2018
6Y24	Crystal structure of fourth KH domain of FUBP1 分子名称: 1,2-ETHANEDIOL, Far upstream element-binding protein 1 著者 Ni, X, Joerger, A.C, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-02-14 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1. Sci Rep, 10, 2020
6JFV	The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14) 分子名称: Keratin, type I cytoskeletal 14, type II cytoskeletal 5 著者 Kim, M.S, Lee, C.H, Coulombe, P.A, Leahy, D.J. 登録日 2019-02-12 公開日 2020-01-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly. Structure, 28, 2020
8DZN	Crystal structure of human Sar1a in complex with GDP 分子名称: GTP-binding protein SAR1a, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.107 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
6Y4S	Human kallikrein-related peptidase 7 (KLK7) in the unliganded state 分子名称: Kallikrein-7, SULFATE ION, TRIETHYLENE GLYCOL 著者 Hanke, S, Strater, N. 登録日 2020-02-23 公開日 2020-05-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7. J.Med.Chem., 63, 2020
6LY4	The crystal structure of the BM3 mutant LG-23 in complex with testosterone 分子名称: 1,2-ETHANEDIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, IMIDAZOLE, ... 著者 Peng, Y, Chen, J, Zhou, J, Li, A, ReetZ, M.T. 登録日 2020-02-13 公開日 2020-04-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angew.Chem.Int.Ed.Engl., 59, 2020
6MEW	RFXANK ankyrin repeats in complex with a RFX7 peptide 分子名称: DNA-binding protein RFXANK, RFX7 peptide, UNKNOWN ATOM OR ION 著者 Tempel, W, Xu, C, Dong, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-09-07 公開日 2018-10-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 RFXANK ankyrin repeats in complex with a RFX7 peptide to be published
8W9J	Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab 分子名称: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A 著者 Mori, S, Nagae, M, Yamasaki, S. 登録日 2023-09-05 公開日 2024-03-06 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024
6LYT	COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 分子名称: HEN EGG WHITE LYSOZYME 著者 Dewan, J.C, Young, A.C.M, Tilton, R.F. 登録日 1992-03-20 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Comparison of Radiation-Induced Decay and Structure Refinement from X-Ray Data Collected from Lysozyme Crystals at Low and Ambient Temperatures J.Appl.Crystallogr., 26, 1993
6LYX	Crystal structure of oxidized ACHT1 分子名称: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... 著者 Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M. 登録日 2020-02-16 公開日 2020-05-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.696 Å) 主引用文献 Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
8DZM	Crystal structure of human Sar1a in complex with ppGpp and Magnesium 分子名称: GTP-binding protein SAR1a, GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.648 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
5Y0G	Crystal structure of human FABP4 complexed with ligand 4-Fluoro-3-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid 分子名称: 4-fluoranyl-3-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte 著者 Su, H.X, Liu, Q.F, Xu, Y.C. 登録日 2017-07-17 公開日 2018-06-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.542 Å) 主引用文献 From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 Eur J Med Chem, 154, 2018
8W8T	Crystal structure of human CLEC12A CRD 分子名称: C-type lectin domain family 12 member A, SULFATE ION 著者 Mori, S, Nagae, M, Yamasaki, S. 登録日 2023-09-04 公開日 2024-03-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024
6M7X	Structure of human CYP11B1 in complex with fadrozole 分子名称: 4-[(5S)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile, Cytochrome P450 11B1, mitochondrial, ... 著者 Scott, E.E, Brixius-Anderko, S. 登録日 2018-08-21 公開日 2018-11-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.095 Å) 主引用文献 Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design. J. Biol. Chem., 294, 2019
8JTT	hOCT1 in complex with metformin in outward occluded conformation 分子名称: Metformin, Solute carrier family 22 member 1 著者 Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. 登録日 2023-06-22 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
8ECR	KRAS4b WT 1-185 bound to GDP-Mg2+ 分子名称: GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Betts, L, Rossman, K.L. 登録日 2022-09-02 公開日 2023-09-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 KRAS4b WT 1-185 bound to GDP-Mg2+ To Be Published
8JTS	hOCT1 in complex with metformin in outward open conformation 分子名称: Metformin, Solute carrier family 22 member 1 著者 Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. 登録日 2023-06-22 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
6J83	Crystal structure of TleB with NMVT 分子名称: Cytochrome P-450, N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-N~2~-methyl-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Fei, H, Mori, T, Abe, I. 登録日 2019-01-18 公開日 2019-08-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
8JU0	hOCT1 in complex with spironolactone in inward facing occluded conformation 分子名称: SPIRONOLACTONE, Solute carrier family 22 member 1 著者 Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. 登録日 2023-06-23 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
5Y4E	Crystal Structure of AnkB Ankyrin Repeats R8-14 in complex with autoinhibition segment AI-b 分子名称: Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION 著者 Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. 登録日 2017-08-03 公開日 2017-09-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017

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