6JFV

The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14)

Summary for 6JFV

Entry DOI	10.2210/pdb6jfv/pdb
Descriptor	Keratin, type I cytoskeletal 14, Keratin, type II cytoskeletal 5 (3 entities in total)
Functional Keywords	intermediate filaments, keratinocytes, skin, epithelium, protein self-assembly, cytosolic protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	45061.58
Authors	Kim, M.S.,Lee, C.H.,Coulombe, P.A.,Leahy, D.J. (deposition date: 2019-02-12, release date: 2020-01-22, Last modification date: 2022-03-23)
Primary citation	Lee, C.H.,Kim, M.S.,Li, S.,Leahy, D.J.,Coulombe, P.A. Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly. Structure, 28:355-362.e4, 2020 Cited by PubMed: 31995743 DOI: 10.1016/j.str.2020.01.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation