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5GN1
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BU of 5gn1 by Molmil
Crystal structure of the C-terminal part of Fun30 ATPase domain
分子名称: ATP-dependent helicase FUN30
著者Jiang, T, Liu, L.
登録日2016-07-18
公開日2017-01-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the ATPase-C domain of the chromatin remodeller Fun30 from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 73, 2017
5C4S
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BU of 5c4s by Molmil
Identification of a Novel Allosteric Binding Site for RORgt Inhibitors
分子名称: 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-4-fluoro-1H-indazol-3-yl}-3-fluorobenzoic acid, GLYCEROL, Nuclear receptor ROR-gamma
著者Parthasarathy, G, Soisson, S.
登録日2015-06-18
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Identification of an allosteric binding site for ROR gamma t inhibition.
Nat Commun, 6, 2015
1RIQ
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BU of 1riq by Molmil
The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
分子名称: Alanyl-tRNA synthetase
著者Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P.
登録日2003-11-17
公開日2004-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
5CKD
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BU of 5ckd by Molmil
E. coli MazF E24A form III
分子名称: Endoribonuclease MazF, SODIUM ION
著者Zorzini, V, Loris, R.
登録日2015-07-15
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.
J.Biol.Chem., 291, 2016
4J1G
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BU of 4j1g by Molmil
Leanyer orthobunyavirus nucleoprotein-ssRNA complex
分子名称: Nucleocapsid, RNA (45-MER)
著者Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
7E0A
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BU of 7e0a by Molmil
X-ray structure of human PPARgamma ligand binding domain-saroglitazar co-crystals obtained by co-crystallization
分子名称: (2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid, Isoform 2 of Peroxisome proliferator-activated receptor gamma
著者Kamata, S, Honda, A, Uchii, K, Machida, Y, Oyama, T, Ishii, I.
登録日2021-01-27
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.771 Å)
主引用文献Structural Basis for Anti-non-alcoholic Fatty Liver Disease and Diabetic Dyslipidemia Drug Saroglitazar as a PPAR alpha / gamma Dual Agonist.
Biol.Pharm.Bull., 44, 2021
7E4W
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BU of 7e4w by Molmil
Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211
分子名称: Activated RNA polymerase II transcriptional coactivator p15
著者Dev, A, Pandey, B, Basu, G.
登録日2021-02-15
公開日2021-09-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules.
Biochem.Biophys.Res.Commun., 578, 2021
1RTY
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BU of 1rty by Molmil
Crystal Structure of Bacillus subtilis YvqK, a putative ATP-binding Cobalamin Adenosyltransferase, The North East Structural Genomics Target SR128
分子名称: PHOSPHATE ION, yvqk protein
著者Forouhar, F, Lee, I, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2003-12-10
公開日2003-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional insights from structural genomics.
J.STRUCT.FUNCT.GENOM., 8, 2007
7E5F
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BU of 7e5f by Molmil
HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH TIPP703 OBTAINED BY SOAKING
分子名称: (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha
著者Oyama, T, Kamata, S, Ishii, I, Miyachi, H.
登録日2021-02-18
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method.
Biol.Pharm.Bull., 44, 2021
7E5G
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BU of 7e5g by Molmil
HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH YN4pai OBTAINED BY SOAKING
分子名称: (2S)-2-[[4-butoxy-3-[(pyren-1-ylcarbonylamino)methyl]phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha
著者Oyama, T, Kamata, S, Ishii, I, Miyachi, H.
登録日2021-02-18
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method.
Biol.Pharm.Bull., 44, 2021
7E5I
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BU of 7e5i by Molmil
HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY SOAKING
分子名称: (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha
著者Oyama, T, Kamata, S, Ishii, I, Miyachi, H.
登録日2021-02-18
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method.
Biol.Pharm.Bull., 44, 2021
7E5H
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BU of 7e5h by Molmil
HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY COCRYSTALLIZATION
分子名称: (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha
著者Oyama, T, Kamata, S, Ishii, I, Miyachi, H.
登録日2021-02-18
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method.
Biol.Pharm.Bull., 44, 2021
5CO7
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BU of 5co7 by Molmil
E. coli MazF form III
分子名称: Endoribonuclease MazF
著者Zorzini, V, Loris, R.
登録日2015-07-19
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.489 Å)
主引用文献Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.
J.Biol.Chem., 291, 2016
1QVF
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BU of 1qvf by Molmil
Structure of a deacylated tRNA minihelix bound to the E site of the large ribosomal subunit of Haloarcula marismortui
分子名称: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
著者Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-27
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
2AO5
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Crystal structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G-U base pairs
分子名称: 5'-R(*GP*GP*CP*GP*(5BU)P*GP*CP*GP*CP*U)-3', MAGNESIUM ION
著者Utsunomiya, R, Suto, K, Balasundaresan, D, Fukamizu, A, Kumar, P.K, Mizuno, H.
登録日2005-08-12
公開日2006-03-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G.U base pairs.
Acta Crystallogr.,Sect.D, 62, 2006
1Q8H
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BU of 1q8h by Molmil
Crystal structure of porcine osteocalcin
分子名称: CALCIUM ION, Osteocalcin
著者Hoang, Q.Q, Sicheri, F, Howard, A.J, Yang, D.S.
登録日2003-08-21
公開日2003-11-11
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bone recognition mechanism of porcine osteocalcin from crystal structure.
Nature, 425, 2003
7PLE
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BU of 7ple by Molmil
ArsH of Paracoccus denitrificans
分子名称: NADPH-dependent FMN reductase
著者Kryl, M.
登録日2021-08-30
公開日2021-10-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The ArsH Protein Product of the Paracoccus denitrificans ars Operon Has an Activity of Organoarsenic Reductase and Is Regulated by a Redox-Responsive Repressor.
Antioxidants, 11, 2022
2B3J
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BU of 2b3j by Molmil
Crystal Structure of Staphylococcus aureus tRNA Adenosine Deaminase, TadA, in Complex with RNA
分子名称: GLYCEROL, ZINC ION, anticodon stem-loop of t-RNA-Arg2 (nucleotides 27-42), ...
著者Losey, H.C, Ruthenburg, A.J, Verdine, G.L.
登録日2005-09-20
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
Nat.Struct.Mol.Biol., 13, 2006
7Q16
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Human 14-3-3 zeta fused to the BAD peptide including phosphoserine-74
分子名称: 14-3-3 protein zeta/delta,Bcl2-associated agonist of cell death
著者Sluchanko, N.N, Tugaeva, K.V, Gushchin, I, Remeeva, A, Kovalev, K, Cooley, R.B.
登録日2021-10-18
公開日2021-11-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.356 Å)
主引用文献Crystal structure of human 14-3-3 zeta complexed with the noncanonical phosphopeptide from proapoptotic BAD.
Biochem.Biophys.Res.Commun., 583, 2021
6EN4
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BU of 6en4 by Molmil
SF3b core in complex with a splicing modulator
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2017-10-04
公開日2018-06-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
Mol. Cell, 70, 2018
2BBF
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BU of 2bbf by Molmil
Crystal structure of tRNA-guanine transglycosylase (TGT) from Zymomonas mobilis in complex with 6-amino-3,7-dihydro-imidazo[4,5-g]quinazolin-8-one
分子名称: 6-AMINO-3,7-DIHYDRO-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ZINC ION, tRNA guanine transglycosylase
著者Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G.
登録日2005-10-17
公開日2007-04-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.
J.Mol.Biol., 370, 2007
5CCA
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BU of 5cca by Molmil
Crystal structure of Mtb toxin
分子名称: Endoribonuclease MazF3
著者Cascio, D, Arbing, M, de Serrano, V, Eisenberg, D, Miallau, L, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-01
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of Mtb toxin
To Be Published
5H1P
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BU of 5h1p by Molmil
CRISPR-associated protein
分子名称: ACETATE ION, CRISPR-associated endoribonuclease Cas2
著者Ka, D, Jeong, U, Bae, E.
登録日2016-10-11
公開日2017-10-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity
Struct Dyn, 4, 2017
7C4O
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Solution structure of the Orange domain from human protein HES1
分子名称: Transcription factor HES-1
著者Fan, J.S, Nayak, A, Swaminathan, K.
登録日2020-05-18
公開日2021-05-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Induction of Transcriptional Inhibitor Hairy and Enhancer of Split Homolog-1 and the Related Repression of Tumor-Suppressor Thioredoxin-Interacting Protein Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase Nucleophosmin-Anaplastic Lymphoma Kinase.
Am J Pathol, 2022
5CK9
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BU of 5ck9 by Molmil
E. coli MazF form I
分子名称: Endoribonuclease MazF, PENTAETHYLENE GLYCOL
著者Zorzini, V, Loris, R.
登録日2015-07-15
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.
J.Biol.Chem., 291, 2016

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