7C4O
Solution structure of the Orange domain from human protein HES1
Summary for 7C4O
| Entry DOI | 10.2210/pdb7c4o/pdb |
| Descriptor | Transcription factor HES-1 (1 entity in total) |
| Functional Keywords | dimer, solution structure, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 10710.28 |
| Authors | Fan, J.S.,Nayak, A.,Swaminathan, K. (deposition date: 2020-05-18, release date: 2021-05-19, Last modification date: 2023-06-14) |
| Primary citation | Zhang, Q.,Wang, H.Y.,Nayak, A.,Nunez-Cruz, S.,Slupianek, A.,Liu, X.,Basappa, J.,Fan, J.S.,Chekol, S.,Nejati, R.,Bogusz, A.M.,Turner, S.D.,Swaminathan, K.,Wasik, M.A. Induction of Transcriptional Inhibitor Hairy and Enhancer of Split Homolog-1 and the Related Repression of Tumor-Suppressor Thioredoxin-Interacting Protein Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase Nucleophosmin-Anaplastic Lymphoma Kinase. Am J Pathol, 2022 Cited by PubMed: 35640677DOI: 10.1016/j.ajpath.2022.05.005 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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