7Q16

Human 14-3-3 zeta fused to the BAD peptide including phosphoserine-74

Summary for 7Q16

Entry DOI	10.2210/pdb7q16/pdb
Descriptor	14-3-3 protein zeta/delta,Bcl2-associated agonist of cell death (2 entities in total)
Functional Keywords	signaling protein, apoptotic regulation, phosphorylation, phosphopeptide binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	27552.87
Authors	Sluchanko, N.N.,Tugaeva, K.V.,Gushchin, I.,Remeeva, A.,Kovalev, K.,Cooley, R.B. (deposition date: 2021-10-18, release date: 2021-11-17, Last modification date: 2024-01-31)
Primary citation	Sluchanko, N.N.,Tugaeva, K.V.,Gushchin, I.,Remeeva, A.,Kovalev, K.,Cooley, R.B. Crystal structure of human 14-3-3 zeta complexed with the noncanonical phosphopeptide from proapoptotic BAD. Biochem.Biophys.Res.Commun., 583:100-105, 2021 Cited by PubMed: 34735870 DOI: 10.1016/j.bbrc.2021.10.053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.356 Å)

Structure validation