6EN4

SF3b core in complex with a splicing modulator

Summary for 6EN4

• Entry DOI: 10.2210/pdb6en4/pdb
• Related: 5IFE
• Descriptor: Splicing factor 3B subunit 3, Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, ... (6 entities in total)
• Functional Keywords: protein complex, splicing modulator, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 254056.34

Authors

Cretu, C.,Pena, V. (deposition date: 2017-10-04, release date: 2018-06-20, Last modification date: 2024-01-17)

• Primary citation: Cretu, C.,Agrawal, A.A.,Cook, A.,Will, C.L.,Fekkes, P.,Smith, P.G.,Luhrmann, R.,Larsen, N.,Buonamici, S.,Pena, V.; Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.; Mol. Cell, 70:265-273.e8, 2018; PubMed: 29656923; DOI: 10.1016/j.molcel.2018.03.011

Experimental method

X-RAY DIFFRACTION (3.08 Å)