6EN4
SF3b core in complex with a splicing modulator
Summary for 6EN4
Entry DOI | 10.2210/pdb6en4/pdb |
Related | 5IFE |
Descriptor | Splicing factor 3B subunit 3, Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, ... (6 entities in total) |
Functional Keywords | protein complex, splicing modulator, splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 254056.34 |
Authors | |
Primary citation | Cretu, C.,Agrawal, A.A.,Cook, A.,Will, C.L.,Fekkes, P.,Smith, P.G.,Luhrmann, R.,Larsen, N.,Buonamici, S.,Pena, V. Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds. Mol. Cell, 70:265-273.e8, 2018 Cited by PubMed: 29656923DOI: 10.1016/j.molcel.2018.03.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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