PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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9F99	Crystal structure of MUS81-EME1 bound by compound 10. 分子名称: 2-(4-chlorophenyl)-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... 著者 Collie, G.W. 登録日 2024-05-07 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024
9F98	Crystal structure of MUS81-EME1, apo form. 分子名称: Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81 著者 Collie, G.W. 登録日 2024-05-07 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024
9F9L	Crystal structure of MUS81-EME1 bound by compound 16. 分子名称: 2-[2-[4-(cyanomethyl)phenyl]phenyl]-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... 著者 Collie, G.W. 登録日 2024-05-07 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024
9F9K	Crystal structure of MUS81-EME1 bound by compound 15. 分子名称: 5-oxidanyl-6-oxidanylidene-2-(4-phenylphenyl)-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... 著者 Collie, G.W. 登録日 2024-05-07 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.728 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024
5XJC	Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 An Atomic Structure of the Human Spliceosome Cell, 169, 2017
9F9M	Crystal structure of MUS81-EME1 bound by compound 21. 分子名称: 5-oxidanyl-4-oxidanylidene-1-(4-piperazin-1-ylphenyl)pyridine-3-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... 著者 Collie, G.W. 登録日 2024-05-08 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.469 Å) 主引用文献 Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024
6BFI	Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution 分子名称: VIN1 著者 Weis, W.I, Chodaparambil, J.V. 登録日 2017-10-26 公開日 2018-06-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution. J. Biol. Chem., 293, 2018
4H1E	Structure of BACE-1 Bound to (7aR)-6-benzoyl-7a-(4-(3-cyanophenyl)thiophen-2-yl)-3-methyl-4-oxohexahydro-1H-pyrrolo[3,4-d]pyrimidin-2(3H)-iminium 分子名称: 3-{5-[(2E,4aR,7aR)-6-benzoyl-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile, Beta-secretase 1 著者 Orth, P. 登録日 2012-09-10 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
5Y04	Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin 分子名称: Catenin alpha-1, Vinculin 著者 Hirano, Y, Hakoshima, T. 登録日 2017-07-14 公開日 2018-03-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form Genes Cells, 23, 2018
1PGS	THE THREE-DIMENSIONAL STRUCTURE OF PNGASE F, A GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM 分子名称: PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F 著者 Norris, G.E, Stillman, T.J, Anderson, B.F, Baker, E.N. 登録日 1994-10-06 公開日 1995-01-26 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum. Structure, 2, 1994
1PNF	PNGASE F COMPLEX WITH DI-N-ACETYLCHITOBIOSE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F, SULFATE ION 著者 Van Roey, P, Kuhn, P. 登録日 1995-10-11 公開日 1996-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F. J.Biol.Chem., 270, 1995
1PPE	THE REFINED 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE BETA-TRYPSIN AND CMTI-I, A TRYPSIN INHIBITOR FROM SQUASH SEEDS (CUCURBITA MAXIMA): TOPOLOGICAL SIMILARITY OF THE SQUASH SEED INHIBITORS WITH THE CARBOXYPEPTIDASE A INHIBITOR FROM POTATOES 分子名称: TRYPSIN, TRYPSIN INHIBITOR CMTI-I 著者 Bode, W, Huber, R. 登録日 1991-10-24 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The refined 2.0 A X-ray crystal structure of the complex formed between bovine beta-trypsin and CMTI-I, a trypsin inhibitor from squash seeds (Cucurbita maxima). Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes FEBS Lett., 242, 1989
1I7X	BETA-CATENIN/E-CADHERIN COMPLEX 分子名称: BETA-CATENIN, EPITHELIAL-CADHERIN 著者 Huber, A.H, Weis, W.I. 登録日 2001-03-10 公開日 2001-05-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001
7UKK	Room-temperature X-ray structure of SARS-CoV-2 main protease in complex with GC-376 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase 著者 Kovalevsky, A, Kneller, D.W, Coates, L. 登録日 2022-04-01 公開日 2022-10-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain. Commun Biol, 5, 2022
1U2A	STEM LOOP IIA FROM U2SNRNA OF SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: RNA (5'-R(P*GP*GP*UP*CP*AP*GP*UP*GP*UP*AP*AP*CP*AP*AP*CP*UP*GP*AP*CP*C)-3') 著者 Stallings, S.C, Moore, P.B. 登録日 1997-08-19 公開日 1998-03-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA. Structure, 5, 1997
1LM7	Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure 分子名称: subdomain of Desmoplakin Carboxy-Terminal domain (DPCT) 著者 Choi, H.J, Park-Snyder, S, Pascoe, L.T, Green, K.J, Weis, W.I. 登録日 2002-04-30 公開日 2002-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure. Nat.Struct.Biol., 9, 2002
1PAX	THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH 3,4-DIHYDRO-5-METHYL-ISOQUINOLINONE 分子名称: 3,4-DIHYDRO-5-METHYL-ISOQUINOLINONE, POLY(ADP-RIBOSE) POLYMERASE 著者 Ruf, A, Schulz, G.E. 登録日 1996-05-06 公開日 1997-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the catalytic fragment of poly(ADP-ribose) polymerase from chicken. Proc.Natl.Acad.Sci.USA, 93, 1996
5GNI	The crystal structure of PECAM-1 IgL1-2 trans-homophilic dimer 分子名称: Platelet endothelial cell adhesion molecule 著者 Hu, M, Zhang, H, Liu, Q, Hao, Q. 登録日 2016-07-21 公開日 2016-12-21 最終更新日 2017-02-01 実験手法 X-RAY DIFFRACTION (3.008 Å) 主引用文献 Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion Sci Rep, 6, 2016
1I7W	BETA-CATENIN/PHOSPHORYLATED E-CADHERIN COMPLEX 分子名称: BETA-CATENIN, CHLORIDE ION, EPITHELIAL-CADHERIN, ... 著者 Huber, A.H, Weis, W.I. 登録日 2001-03-10 公開日 2001-05-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001
3RF2	Crystal Structure of 30S Ribosomal Protein S8 from Aquifex Aeolicus 分子名称: 30S ribosomal protein S8, SULFATE ION 著者 Menichelli, E, Williamson, J.R. 登録日 2011-04-05 公開日 2011-11-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 The Structure of Aquifex aeolicus Ribosomal Protein S8 Reveals a Unique Subdomain that Contributes to an Extremely Tight Association with 16S rRNA. J.Mol.Biol., 415, 2012
5FD1	CRYSTAL STRUCTURES OF OXIDIZED AND REDUCED AZOTOBACTER VINELANDII FERREDOXIN AT PH 8 AND PH 6 分子名称: FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER 著者 Stout, C.D. 登録日 1993-06-29 公開日 1993-10-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of oxidized and reduced Azotobacter vinelandii ferredoxin at pH 8 and 6. J.Biol.Chem., 268, 1993
1P4E	Flpe W330F mutant-DNA Holliday Junction Complex 分子名称: 33-MER, 5'-D(*TP*AP*AP*GP*TP*TP*CP*CP*TP*AP*TP*TP*C)-3', 5'-D(*TP*TP*TP*AP*AP*AP*AP*GP*AP*AP*TP*AP*GP*GP*AP*AP*CP*TP*TP*C)-3', ... 著者 Rice, P.A, Chen, Y. 登録日 2003-04-23 公開日 2003-05-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The role of the conserved Trp330 in Flp-mediated recombination. Functional and structural analysis J.Biol.Chem., 278, 2003
3ZBO	A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures 分子名称: ALKF, CHLORIDE ION 著者 Backe, P.H, Simm, R, Laerdahl, J.K, Dalhus, B, Fagerlund, A, Okstad, O.A, Rognes, T, Alseth, I, Kolsto, A.-B, Bjoras, M. 登録日 2012-11-12 公開日 2013-05-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A New Family of Proteins Related to the Heat-Like Repeat DNA Glycosylases with Affinity for Branched DNA Structures. J.Struct.Biol., 183, 2013
1LM5	Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure 分子名称: subdomain of Desmoplakin Carboxy-Terminal domain (DPCT) 著者 Choi, H.J, Park-Snyder, S, Pascoe, L.T, Green, K.J, Weis, W.I. 登録日 2002-04-30 公開日 2002-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure. Nat.Struct.Biol., 9, 2002
4BOO	The structure and super-organization of acetylcholine receptor-rapsyn complexes class C 分子名称: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ... 著者 Zuber, B, Unwin, N. 登録日 2013-05-21 公開日 2013-06-26 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (42 Å) 主引用文献 Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes. Proc.Natl.Acad.Sci.USA, 110, 2013

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