9F98

Crystal structure of MUS81-EME1, apo form.

Summary for 9F98

Entry DOI	10.2210/pdb9f98/pdb
Descriptor	Crossover junction endonuclease MUS81, Crossover junction endonuclease EME1 (3 entities in total)
Functional Keywords	mus81-eme1, fragment, inhibitor, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	140608.17
Authors	Collie, G.W. (deposition date: 2024-05-07, release date: 2024-07-03)
Primary citation	Collie, G.W.,Borjesson, U.,Chen, Y.,Dong, Z.,Di Fruscia, P.,Gohlke, A.,Hoyle, A.,Hunt, T.A.,Jesani, M.H.,Luo, H.,Luptak, J.,Milbradt, A.G.,Narasimhan, P.,Packer, M.,Patel, S.,Qiao, J.,Storer, R.I.,Stubbs, C.J.,Tart, J.,Truman, C.,Wang, A.T.,Wheeler, M.G.,Winter-Holt, J. Fragment-Based Discovery of Novel MUS81 Inhibitors Acs Med.Chem.Lett., 2024 Cited by DOI: 10.1021/acsmedchemlett.3c00453 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation