PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

---

4R8T	Structure of JEV protease 分子名称: CHLORIDE ION, NS3, Serine protease subunit NS2B 著者 Nair, D.T, Weinert, T, Wang, M, Olieric, V. 登録日 2014-09-03 公開日 2014-12-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.133 Å) 主引用文献 Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
2P1U	Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-ethoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2 分子名称: (2E)-3-[3-(3-ETHOXY-5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-4-HYDROXYPHENYL]ACRYLIC ACID, Nuclear receptor coactivator 2 peptide, Retinoic acid receptor RXR-alpha 著者 Bourguet, W, Nahoum, V. 登録日 2007-03-06 公開日 2007-10-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc.Natl.Acad.Sci.Usa, 104, 2007
4XX8	Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2015-01-30 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
3LLM	Crystal Structure Analysis of a RNA Helicase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, CACODYLATE ION, ... 著者 Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) 登録日 2010-01-29 公開日 2010-05-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein. J.Mol.Biol., 400, 2010
4Y1C	Cyclic hexapeptide cyc[NdPopPKID] in complex with HIV-1 integrase core domain 分子名称: CADMIUM ION, Cyclic hexapeptide cyc[NdPopPKID], Integrase, ... 著者 Wielens, J, Chalmers, D.K. 登録日 2015-02-07 公開日 2015-02-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 HEXAPEPTIDE MIMETICS OF LEDGF IN COMPLEX WITH HIV-1 INTEGRASE To Be Published
5PC4	PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 25) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-03 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PCR	PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 48) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-03 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PDA	PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 66) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-03 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PDO	PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 81) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-03 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
5PE3	PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 96) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-03 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
4XX7	Crystal structure of M2A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-01-29 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
5O4T	Crystal structure of the human BRPF1 bromodomain in complex with BZ061 分子名称: 1,4-dimethylquinoxaline-2,3-dione, Peregrin 著者 Zhu, J, Caflisch, A. 登録日 2017-05-30 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-based discovery of selective BRPF1 bromodomain inhibitors. Eur J Med Chem, 155, 2018
4Y1D	Cyclic hexapeptide cyc[NdPopPKID] in complex with HIV-1 integrase core domain 分子名称: CADMIUM ION, CHLORIDE ION, Cyclic hexapeptide cyc[NdPopPKID], ... 著者 Wielens, J, Chalmers, D.K. 登録日 2015-02-07 公開日 2015-05-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 HEXAPEPTIDE MIMETICS OF LEDGF IN COMPLEX WITH HIV-1 INTEGRASE To Be Published
2QPY	AR LBD with small molecule 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Coactivator peptide, ... 著者 Estebanez-Perpina, E, Fletterick, R. 登録日 2007-07-25 公開日 2007-09-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A surface on the androgen receptor that allosterically regulates coactivator binding. Proc.Natl.Acad.Sci.Usa, 104, 2007
1NGU	NMR Structure of Putative 3'Terminator for B. Anthracis pagA Gene Noncoding Strand 分子名称: 5'-D(*CP*TP*CP*TP*CP*CP*TP*TP*GP*TP*AP*TP*TP*TP*CP*TP*TP*AP*CP*AP*AP*AP*AP*AP*GP*AP*G)-3' 著者 Shiflett, P.R, Taylor-McCabe, K.J, Michalczyk, R, Silks, L.A, Gupta, G. 登録日 2002-12-17 公開日 2003-06-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural Studies on the Hairpins at the 3' Untranslated Region of an Anthrax Toxin Gene Biochemistry, 42, 2003
4RE1	Crystal structure of human TEAD1 and disulfide-engineered YAP 分子名称: CHLORIDE ION, Transcriptional enhancer factor TEF-1, Yorkie homolog 著者 Xu, Z, Zhou, Z. 登録日 2014-09-21 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides. Faseb J., 29, 2015
7R72	State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model 分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-24 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
2RCW	PARP complexed with A620223 分子名称: Poly [ADP-ribose] polymerase 1, trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium 著者 Park, C.H. 登録日 2007-09-20 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 PARP complexed with A620223 To be Published
2RFI	Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide 分子名称: Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... 著者 Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2007-09-30 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
7WU7	Prefoldin-tubulin-TRiC complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... 著者 Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. 登録日 2022-02-07 公開日 2022-12-21 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
4RHP	Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043 分子名称: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, mitochondrial 著者 Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Lee, D, Kogan, S, Maglaqui, M, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) 登録日 2014-10-02 公開日 2014-10-22 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proc.Natl.Acad.Sci.USA, 111, 2014
6RA4	Human ARGONAUTE-2 PAZ DOMAIN (214-347) IN COMPLEX WITH CGUGACUCU 分子名称: GLYCEROL, Protein argonaute-2, RNA (5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3') 著者 Rondeau, J.-M, Bourgier, E. 登録日 2019-04-05 公開日 2019-05-08 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for de Novo siRNA Guide Strand Surrogate Selection. J.Chem.Inf.Model., 59, 2019
7B7D	Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... 著者 Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N. 登録日 2020-12-10 公開日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome To Be Published
7E73	Crystal structure of human ERK2 mutant (Y36H) 分子名称: Mitogen-activated protein kinase 1, SULFATE ION 著者 Park, Y.S, Kim, M, Ryu, S.E. 登録日 2021-02-25 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural mechanism of inhibitor-resistance by ERK2 mutations Biodesign, 9, 2021
5OK6	Ubiquitin specific protease 11 USP11 - peptide F complex 分子名称: 1,2-ETHANEDIOL, ALA-GLU-GLY-GLU-PHE-TYR-LYS-LEU-LYS-ILE-ARG-THR-PRO-AAR, GLYCEROL, ... 著者 Spiliotopoulos, A, Dreveny, I. 登録日 2017-07-25 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11. J.Biol.Chem., 294, 2019

<1179118011811182118311841185118611871188118911901191119211931194>