2OBJ
 
 | | Crystal structure of human PIM-1 Kinase in complex with inhibitor | | 分子名称: | 6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE, Proto-oncogene serine/threonine-protein kinase Pim-1 | | 著者 | Yao, N, Cheney, I.W, Yan, S. | | 登録日 | 2006-12-19 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.
Bioorg.Med.Chem.Lett., 17, 2007
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2HK8
 | | Crystal structure of shikimate dehydrogenase from aquifex aeolicus at 2.35 angstrom resolution | | 分子名称: | Shikimate dehydrogenase | | 著者 | Gan, J.H, Prabakaran, P, Gu, Y.J, Andrykovitch, M, Li, Y, Liu, H.H, Yan, H, Ji, X. | | 登録日 | 2006-07-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.
Biochemistry, 46, 2007
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2HK7
 | | Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with mercury at 2.5 angstrom resolution | | 分子名称: | MERCURY (II) ION, Shikimate dehydrogenase | | 著者 | Gan, J.H, Prabakaran, P, Gu, Y.J, Andrykovitch, M, Li, Y, Liu, H.H, Yan, H, Ji, X. | | 登録日 | 2006-07-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.
Biochemistry, 46, 2007
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2KA4
 | | NMR structure of the CBP-TAZ1/STAT2-TAD complex | | 分子名称: | Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION | | 著者 | Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | 登録日 | 2008-10-30 | | 公開日 | 2009-04-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
Embo J., 28, 2009
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2V85
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2EZ6
 | | Crystal structure of Aquifex aeolicus RNase III (D44N) complexed with product of double-stranded RNA processing | | 分子名称: | 28-MER, MAGNESIUM ION, Ribonuclease III | | 著者 | Gan, J, Tropea, J.E, Austin, B.P, Court, D.L, Waugh, D.S, Ji, X. | | 登録日 | 2005-11-10 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III.
Cell(Cambridge,Mass.), 124, 2006
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2HRO
 | | Structure of the full-lenght Enzyme I of the PTS system from Staphylococcus carnosus | | 分子名称: | Phosphoenolpyruvate-protein phosphotransferase, SULFATE ION | | 著者 | Marquez, J.A, Reinelt, S, Koch, B, Engelman, R, Hengstenberg, W, Scheffzek, K. | | 登録日 | 2006-07-20 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the full-length enzyme I of the phosphoenolpyruvate-dependent sugar phosphotransferase system
J.Biol.Chem., 281, 2006
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2HM1
 | | Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2) | | 分子名称: | Beta-secretase 1, N-{(1S)-2-({(1S,2R)-1-(3,5-DIFLUOROBENZYL)-3-[(3-ETHYLBENZYL)AMINO]-2-HYDROXYPROPYL}AMINO)-2-OXO-1-[(PENTYLSULFONYL)METHYL]ETHYL}NICOTINAMIDE | | 著者 | Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J. | | 登録日 | 2006-07-10 | | 公開日 | 2007-01-23 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design of potent inhibitors of human beta-secretase. Part 2.
Bioorg.Med.Chem.Lett., 17, 2007
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2V88
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2V86
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2DR7
 | | Complex structure of CCA-adding enzyme with tRNAminiDC | | 分子名称: | CCA-adding enzyme, SULFATE ION, tRNA (33-MER) | | 著者 | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | | 登録日 | 2006-06-08 | | 公開日 | 2006-11-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
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2DVI
 | | Complex structure of CCA-adding enzyme, mini-DCC and CTP | | 分子名称: | CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | | 登録日 | 2006-07-31 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
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2DOR
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2EEW
 | | Guanine Riboswitch U47C mutant bound to hypoxanthine | | 分子名称: | ACETATE ION, COBALT HEXAMMINE(III), Guanine riboswitch, ... | | 著者 | Gilbert, S.D, Love, C.E, Batey, R.T. | | 登録日 | 2007-02-19 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mutational analysis of the purine riboswitch aptamer domain
Biochemistry, 46, 2007
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2E5L
 | | A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine- Dalgarno interaction | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Kaminishi, T, Wilson, D.N, Takemoto, C, Harms, J.M, Kawazoe, M, Schluenzen, F, Hanawa-Suetsugu, K, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-12-21 | | 公開日 | 2007-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
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2EF4
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2E9W
 | | Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor | | 著者 | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | | 登録日 | 2007-01-27 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
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2O3P
 | | Crystal structure of Pim1 with Quercetin | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1 | | 著者 | Holder, S, Zemskova, M, Zhang, C, Tabrizizad, M, Bremer, R, Neidigh, J.W, Lilly, M.B. | | 登録日 | 2006-12-01 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Mol.Cancer Ther., 6, 2007
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2O4F
 | | Structure of a parallel-stranded guanine tetraplex crystallised with monovalent ions | | 分子名称: | 5'-D(*TP*GP*GP*GP*GP*T)-3', LITHIUM ION, SODIUM ION | | 著者 | Creze, C, Rinaldi, B, Haser, R, Bouvet, P, Gouet, P. | | 登録日 | 2006-12-04 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions.
Acta Crystallogr.,Sect.D, 63, 2007
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2O65
 | | Crystal structure of Pim1 with Pentahydroxyflavone | | 分子名称: | 5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1 | | 著者 | Holder, S, Zemskova, M, Zhang, C, Tabrizizad, M, Bremer, R, Neidigh, J.W, Lilly, M.B. | | 登録日 | 2006-12-06 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Mol.Cancer Ther., 6, 2007
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2O64
 | | Crystal structure of Pim1 with Quercetagetin | | 分子名称: | 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1 | | 著者 | Holder, S, Zemskova, M, Zhang, C, Tabrizizad, M, Bremer, R, Neidigh, J.W, Lilly, M.B. | | 登録日 | 2006-12-06 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Mol.Cancer Ther., 6, 2007
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2NRN
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2HW8
 | | Structure of ribosomal protein L1-mRNA complex at 2.1 resolution. | | 分子名称: | 1,4-BUTANEDIOL, 36-MER, 50S ribosomal protein L1, ... | | 著者 | Tishchenko, S, Nikonova, E, Nikulin, A, Nevskaya, N, Volchkov, S, Piendl, W, Garber, M, Nikonov, S. | | 登録日 | 2006-08-01 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the ribosomal protein L1-mRNA complex at 2.1 A resolution: common features of crystal packing of L1-RNA complexes.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2HWM
 | | Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution | | 分子名称: | FORMIC ACID, Heparin-binding growth factor 1 | | 著者 | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | 登録日 | 2006-08-01 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2DRA
 | | Complex structure of CCA-adding enzyme with tRNAminiDCC and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ... | | 著者 | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | | 登録日 | 2006-06-08 | | 公開日 | 2006-11-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
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