PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6VLR	BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2 gp41, ... 著者 Cottrell, C.A, Ward, A.B. 登録日 2020-01-24 公開日 2020-06-24 最終更新日 2020-09-16 実験手法 ELECTRON MICROSCOPY (4.42 Å) 主引用文献 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathog., 16, 2020
6VK8	Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex with small organic carboxylate at active center 分子名称: 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... 著者 Jones, J.C, Banerjee, R, Shi, K, Aihara, H, Lipscomb, J.D. 登録日 2020-01-18 公開日 2020-08-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural Studies of theMethylosinus trichosporiumOB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel. Biochemistry, 59, 2020
7SPB	Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by F-plasmid (pED208). 分子名称: TraB, TraK, TraV 著者 Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B. 登録日 2021-11-02 公開日 2022-02-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids Nat Commun, 13, 2022
7STZ	Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-15 公開日 2022-01-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1, 2022
6VLX	Crystal structure of FabI from Alistipes finegoldii 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL 著者 Radka, C.D, Seetharaman, J, Rock, C.O. 登録日 2020-01-27 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI). J.Biol.Chem., 295, 2020
7SPI	Models for C13 reconstruction of Outer Membrane Core Complex (OMCC) of Type IV Secretion System (T4SS) encoded by a plasmid overproducing TraV, TraK and TraB of pED208 分子名称: TraB, TraK, TraV 著者 Liu, X, Khara, P, Baker, M.L, Christie, P.J, Hu, B. 登録日 2021-11-02 公開日 2022-02-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids Nat Commun, 13, 2022
7TEI	SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Stalls, V, Acharya, P. 登録日 2022-01-05 公開日 2022-02-16 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
6VMK	Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 分子名称: Complement factor D, Fab Y49R heavy chain, Fab Y49R light chain, ... 著者 Wu, P, Harris, S.F, Eigenbrot, C. 登録日 2020-01-28 公開日 2021-02-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 To Be Published
7TF8	SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Stalls, V, Acharya, P. 登録日 2022-01-06 公開日 2022-02-16 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
7SSW	Late translocation intermediate with EF-G dissociated (Structure VI) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
6VRK	Cryo-EM structure of the wild-type human serotonin transporter complexed with Br-paroxetine and 8B6 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... 著者 Coleman, J.A, Navratna, V, Yang, D. 登録日 2020-02-07 公開日 2020-03-11 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
7SSN	Pre translocation 70S ribosome with A/P* and P/E tRNA (Structure II-B) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SS9	Late translocation intermediate with EF-G partially dissociated (Structure V) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A. 登録日 2021-11-10 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST6	Pre translocation, non-rotated 70S ribosome (Structure I) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-12 公開日 2022-02-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST7	Pre translocation intermediate stalled with viomycin and bound with EF-G in a GDP and Pi state (Structure III-vio) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-12 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST2	Post translocation, non-rotated 70S ribosome with EF-G dissociated (Structure VII) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SSL	Pre translocation intermediate with EF-G bound to GDP and Pi (Structure III) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
8BFL	Jumbo Phage phi-kp24 empty capsid hexamers 分子名称: Major head protein 著者 Ouyang, R. 登録日 2022-10-26 公開日 2022-12-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers. Nat Commun, 13, 2022
7U2I	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-02-24 公開日 2022-07-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
6VWN	70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure II) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. 登録日 2020-02-20 公開日 2020-06-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding. Elife, 9, 2020
7U2J	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-02-24 公開日 2022-07-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
6VZ5	Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Wang, C, Su, M, Ebright, R.H. 登録日 2020-02-27 公開日 2020-09-02 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (8.9 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
6VU3	Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Wang, C, Su, M, Ebright, R. 登録日 2020-02-14 公開日 2020-09-02 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
7TSK	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-methyl-6-[3-(methylamino)prop-1-yn-1-yl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2022-01-31 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors. Bioorg.Med.Chem., 69, 2022
8BSD	SARS-CoV-2 nsp10-16 methyltransferase in complex with tubercidin 分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, ... 著者 Kremling, V, Oberthuer, D, Sprenger, J. 登録日 2022-11-24 公開日 2022-12-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structures of Tubercidin bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16 To Be Published

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