8W8D
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5ELY
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![BU of 5ely by Molmil](/molmil-images/mine/5ely) | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU242 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2~{R})-2-carboxy-5-(oxidanylamino)-5-oxidanylidene-pentyl]benzoic acid, ... | 著者 | Barinka, C, Novakova, Z, Pavlicek, J. | 登録日 | 2015-11-05 | 公開日 | 2016-04-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity. J.Med.Chem., 59, 2016
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8WPZ
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7R85
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5GKH
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![BU of 5gkh by Molmil](/molmil-images/mine/5gkh) | Structure of EndoMS-dsDNA2 complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*TP*TP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*CP*CP*AP*GP*GP*TP*GP*CP*CP*GP*T)-3'), ... | 著者 | Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T. | 登録日 | 2016-07-04 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease Structure, 24, 2016
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4IDB
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![BU of 4idb by Molmil](/molmil-images/mine/4idb) | Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ | 分子名称: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ripening-induced protein, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
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4NAT
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![BU of 4nat by Molmil](/molmil-images/mine/4nat) | Inhibitors of 4-Phosphopanthetheine Adenylyltransferase | 分子名称: | (1R,2R)-N-(3,4-dichlorobenzyl)-2-(4,6-dimethoxypyrimidin-2-yl)cyclohexanecarboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Lahiri, S.D. | 登録日 | 2013-10-22 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Discovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy. Antimicrob.Agents Chemother., 57, 2013
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4IE6
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2X23
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![BU of 2x23 by Molmil](/molmil-images/mine/2x23) | crystal structure of M. tuberculosis InhA inhibited by PT70 | 分子名称: | 5-HEXYL-2-(2-METHYLPHENOXY)PHENOL, DIMETHYL SULFOXIDE, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], ... | 著者 | Luckner, S.R, Liu, N, am Ende, C.W, Tonge, P.J, Kisker, C. | 登録日 | 2010-01-10 | 公開日 | 2010-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.807 Å) | 主引用文献 | A Slow, Tight Binding Inhibitor of Inha, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium Tuberculosis. J.Biol.Chem., 285, 2010
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7K3R
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8VSP
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![BU of 8vsp by Molmil](/molmil-images/mine/8vsp) | Cryo-EM structure of human invariant chain in complex with HLA-DQ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-24 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
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2CMD
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2CAR
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![BU of 2car by Molmil](/molmil-images/mine/2car) | Crystal Structure Of Human Inosine Triphosphatase | 分子名称: | INOSINE TRIPHOSPHATE PYROPHOSPHATASE | 著者 | Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P. | 登録日 | 2005-12-22 | 公開日 | 2006-01-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T. J.Biol.Chem., 282, 2007
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3AUJ
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![BU of 3auj by Molmil](/molmil-images/mine/3auj) | Structure of diol dehydratase complexed with glycerol | 分子名称: | CALCIUM ION, COBALAMIN, Diol dehydrase alpha subunit, ... | 著者 | Yamanishi, M, Kinoshita, K, Fukuoka, M, Shibata, T, Tobimatsu, T, Toraya, T. | 登録日 | 2011-02-07 | 公開日 | 2012-02-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols Febs J., 279, 2012
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4LGH
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5DAZ
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7KCJ
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5DB3
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![BU of 5db3 by Molmil](/molmil-images/mine/5db3) | Menin in complex with MI-574 | 分子名称: | 6-methoxy-4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Pollock, J, Borkin, D, Cierpicki, T, Grembecka, J. | 登録日 | 2015-08-20 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL). J.Med.Chem., 59, 2016
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4LHC
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![BU of 4lhc by Molmil](/molmil-images/mine/4lhc) | Crystal structure of Synechocystis sp. PCC 6803 glycine decarboxylase (P-protein), holo form with pyridoxal-5'-phosphate and glycine | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, BICINE, ... | 著者 | Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I. | 登録日 | 2013-07-01 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation. J.Biol.Chem., 288, 2013
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4LIW
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7JSR
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![BU of 7jsr by Molmil](/molmil-images/mine/7jsr) | Crystal structure of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis | 分子名称: | NAD-specific glutamate dehydrogenase | 著者 | Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N. | 登録日 | 2020-08-15 | 公開日 | 2021-06-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (6.27 Å) | 主引用文献 | 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme. Commun Biol, 4, 2021
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7RHE
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5GM7
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![BU of 5gm7 by Molmil](/molmil-images/mine/5gm7) | Crystal structure of Ribosome inactivating protein from Momordica balsamina at 1.78 Angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Ribosome inactivating protein | 著者 | Singh, B, Singh, P.K, Pandey, S.N, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2016-07-13 | 公開日 | 2016-07-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of Ribosome inactivating protein from Momordica balsamina at 1.78 Angstrom resolution To Be Published
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8VRW
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![BU of 8vrw by Molmil](/molmil-images/mine/8vrw) | Cryo-EM structure of human invariant chain in complex with HLA-DR15 | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-22 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
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7JOF
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![BU of 7jof by Molmil](/molmil-images/mine/7jof) | Calcium-bound C2A Domain from Human Dysferlin | 分子名称: | CALCIUM ION, Isoform 6 of Dysferlin | 著者 | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | 登録日 | 2020-08-06 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem.J., 478, 2021
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