2CAR

Crystal Structure Of Human Inosine Triphosphatase

Summary for 2CAR

DescriptorINOSINE TRIPHOSPHATE PYROPHOSPHATASE (2 entities in total)
Functional Keywordshydrolase, inosine triphosphate pyrophosphohydrolase, inosine triphosphatase deficiency, itp, imp, disease mutation, nucleotide metabolism
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight43225.51
Authors
Primary citation
Stenmark, P.,Kursula, P.,Flodin, S.,Graslund, S.,Landry, R.,Nordlund, P.,Schuler, H.
Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282:3182-, 2007
PubMed: 17138556 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M609838200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.09 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1558 1.0% 3.4% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report