2CAR

Crystal Structure Of Human Inosine Triphosphatase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006193	biological_process	ITP catabolic process
A	0009117	biological_process	nucleotide metabolic process
A	0009143	biological_process	nucleoside triphosphate catabolic process
A	0009204	biological_process	deoxyribonucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0035870	molecular_function	dITP diphosphatase activity
A	0036220	molecular_function	ITP diphosphatase activity
A	0036222	molecular_function	XTP diphosphatase activity
A	0042802	molecular_function	identical protein binding
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0046872	molecular_function	metal ion binding
A	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
A	0051276	biological_process	chromosome organization
B	0000166	molecular_function	nucleotide binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006193	biological_process	ITP catabolic process
B	0009117	biological_process	nucleotide metabolic process
B	0009143	biological_process	nucleoside triphosphate catabolic process
B	0009204	biological_process	deoxyribonucleoside triphosphate catabolic process
B	0016787	molecular_function	hydrolase activity
B	0035870	molecular_function	dITP diphosphatase activity
B	0036220	molecular_function	ITP diphosphatase activity
B	0036222	molecular_function	XTP diphosphatase activity
B	0042802	molecular_function	identical protein binding
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0046872	molecular_function	metal ion binding
B	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
B	0051276	biological_process	chromosome organization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:17138556, ECO:0007744|PDB:2J4E

Chain	Residue	Details
A	THR14
B	GLU44
B	LYS56
B	ASP72
B	LYS89
B	PHE149
B	LYS172
B	HIS177
A	GLU44
A	LYS56
A	ASP72
A	LYS89
A	PHE149
A	LYS172
A	HIS177
B	THR14

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N-acetylalanine => ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|Ref.9

Chain	Residue	Details
A	ALA2
B	ALA2

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