PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

---

2R8G	Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DT)-3', 5'-D(*DTP*DCP*DAP*DCP*(P)P*DGP*DAP*DAP*DAP*DTP*DCP*DCP*DTP*DTP*DCP*DCP*DCP*DCP*DC)-3', ... 著者 Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. 登録日 2007-09-10 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV Biochemistry, 47, 2008
4USU	Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate 分子名称: 1,2-ETHANEDIOL, ADENYLATE CYCLASE TYPE 10, CALCIUM ION, ... 著者 Kleinboelting, S, Steegborn, C. 登録日 2014-07-13 公開日 2014-07-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution. FEBS J., 281, 2014
6PLN	X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha 分子名称: Transcription factor E 著者 Murakami, K.S, Jun, S.H. 登録日 2019-07-01 公開日 2020-07-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
6P78	queuine lyase from Clostridium spiroforme bound to SAM and queuine 分子名称: 2-amino-5-({[(1S,4S,5S)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, IRON/SULFUR CLUSTER, Queuine lyase, ... 著者 Almo, S.C, Grove, T.L. 登録日 2019-06-05 公開日 2019-09-18 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.726 Å) 主引用文献 Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens. Proc.Natl.Acad.Sci.USA, 116, 2019
6PAL	Bacteroides uniformis endo-laminarinase BuGH158 from the beta(1,3)-glucan utilization locus 分子名称: ACETATE ION, SULFATE ION, Uncharacterized protein 著者 Tamura, K, Brumer, H, van Petegem, F. 登録日 2019-06-11 公開日 2020-04-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.818 Å) 主引用文献 Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human GutBacteroides. Mbio, 11, 2020
6X1Z	Mre11 dimer in complex with small molecule modulator PFMJ 分子名称: (5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... 著者 Arvai, A.S, Moiani, D, Tainer, J.A. 登録日 2020-05-19 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response. Prog.Biophys.Mol.Biol., 163, 2021
2UW9	STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH 4-(4-chloro-phenyl)-4-(4-(1H-pyrazol-4-yl)-phenyl)-piperidine 分子名称: 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE, GLYCOGEN SYNTHASE KINASE-3 BETA, RAC-BETA SERINE/THREONINE-PROTEIN KINASE 著者 Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A. 登録日 2007-03-19 公開日 2007-05-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery. J.Med.Chem., 50, 2007
6X1Y	Mre11 dimer in complex with small molecule modulator PFMI 分子名称: (5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclease SbcCD subunit D 著者 Arvai, A.S, Moiani, D, Tainer, J.A. 登録日 2020-05-19 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response. Prog.Biophys.Mol.Biol., 163, 2021
6V2E	Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant 分子名称: ADM, AMINO GROUP, FORMIC ACID, ... 著者 Booe, J.M, Pioszak, A.A. 登録日 2019-11-22 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors. Acs Pharmacol Transl Sci, 3, 2020
3D55	Crystal structure of M. tuberculosis YefM antitoxin 分子名称: SULFATE ION, Uncharacterized protein Rv3357/MT3465 著者 Kumar, P, Issac, B, Dodson, E.J, Turkenberg, J.P, Mande, S.C. 登録日 2008-05-15 公開日 2008-12-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein J.Mol.Biol., 383, 2008
3CP8	Crystal structure of GidA from Chlorobium tepidum 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA 著者 Meyer, S, Scrima, A, Versees, W, Wittinghofer, A. 登録日 2008-03-31 公開日 2008-06-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate J.Mol.Biol., 380, 2008
3CTO	Crystal Structure of M. tuberculosis YefM antitoxin 分子名称: SULFATE ION, Uncharacterized protein Rv3357/MT3465 著者 Kumar, P, Issac, B, Dodson, E.J, Turkenberg, J.P, Mande, S.C. 登録日 2008-04-14 公開日 2008-12-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein J.Mol.Biol., 383, 2008
6FVS	The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Barium ions (Ba2+) 分子名称: BARIUM ION, Cys-loop ligand-gated ion channel, ZINC ION, ... 著者 Hu, H, Delarue, M. 登録日 2018-03-05 公開日 2018-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3LC6	The alternative conformation structure of isocitrate dehydrogenase kinase/phosphatase from E. Coli 分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ... 著者 Zheng, J, Jia, Z. 登録日 2010-01-09 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase. Nature, 465, 2010
3CP2	Crystal structure of GidA from E. coli 分子名称: SULFATE ION, tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA 著者 Scrima, A, Meyer, S, Versees, W, Wittinghofer, A. 登録日 2008-03-30 公開日 2008-06-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate J.Mol.Biol., 380, 2008
3CIO	The kinase domain of Escherichia coli tyrosine kinase ETK 分子名称: CHLORIDE ION, Tyrosine-protein kinase etk 著者 Lee, D.C, Zheng, J, Jia, Z. 登録日 2008-03-11 公開日 2008-06-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism. Embo J., 27, 2008
6FVQ	The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A 分子名称: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside 著者 Hu, H, Delarue, M. 登録日 2018-03-05 公開日 2018-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-16 公開日 2012-10-17 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
4G2U	Crystal Structure Analysis of Ostertagia ostertagi ASP-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ancylostoma-secreted protein-like protein, SULFATE ION 著者 Weeks, S.D, Borloo, J, Geldhof, P, Vercruysse, J, Strelkov, S.V. 登録日 2012-07-13 公開日 2013-03-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of Ostertagia ostertagi ASP-1: insights into disulfide-mediated cyclization and dimerization Acta Crystallogr.,Sect.D, 69, 2013
5ZZB	LokiProfilin2/Rabbit Actin Complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Robinson, R.C, Akil, C. 登録日 2018-05-31 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Genomes of Asgard archaea encode profilins that regulate actin. Nature, 562, 2018
8YV8	Cryo-EM structure of CDCA7 bound to nucleosome including hemimethylated CpG site in Widom601 positioning sequence. 分子名称: Cell division cycle-associated protein 7, DNA (132-MER), Histone H2A type 1-B/E, ... 著者 Kikuchi, A, Shikimachi, R, Nishiyama, A, Funabiki, H, Arita, K. 登録日 2024-03-28 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 CDCA7 is a hemimethylated DNA adaptor for the nucleosome remodeler HELLS To Be Published
3MBF	Crystal structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi, bound to fructose 1,6-bisphosphate 分子名称: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), Fructose-bisphosphate aldolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-25 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi. Acta Crystallogr.,Sect.F, 67, 2011
4QFG	Structure of AMPK in complex with STAUROSPORINE inhibitor and in the absence of a synthetic activator 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Calabrese, M.F, Kurumbail, R.G. 登録日 2014-05-20 公開日 2014-08-06 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms. Structure, 22, 2014
5ZZA	OdinProfilin/Rabbit Actin Complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Robinson, R.C, Akil, C. 登録日 2018-05-31 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Genomes of Asgard archaea encode profilins that regulate actin. Nature, 562, 2018
4QFR	Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor 分子名称: 2-chloro-4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... 著者 Calabrese, M.F, Kurumbail, R.G. 登録日 2014-05-21 公開日 2014-08-06 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms. Structure, 22, 2014

<1106110711081109111011111112111311141115111611171118111911201121>