Summary for 6P78
| Descriptor | Queuine lyase, IRON/SULFUR CLUSTER, 2-amino-5-({[(1S,4S,5S)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ... (5 entities in total) |
|---|---|
| Functional Keywords | metal ion binding, 4 iron 4 sulfur cluster binding, radical sam enzyme, c-n lyase activity, lyase |
| Biological source | [Clostridium] spiroforme DSM 1552 |
| Total number of polymer chains | 1 |
| Total molecular weight | 30961.44 |
| Authors | Almo, S.C.,Grove, T.L. (deposition date: 2019-06-05, release date: 2019-09-18, Last modification date: 2019-12-18) |
| Primary citation | Yuan, Y.,Zallot, R.,Grove, T.L.,Payan, D.J.,Martin-Verstraete, I.,Sepic, S.,Balamkundu, S.,Neelakandan, R.,Gadi, V.K.,Liu, C.F.,Swairjo, M.A.,Dedon, P.C.,Almo, S.C.,Gerlt, J.A.,de Crecy-Lagard, V. Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens. Proc.Natl.Acad.Sci.USA, 116:19126-19135, 2019 PubMed: 31481610 (PDB entries with the same primary citation) DOI: 10.1073/pnas.1909604116  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.726 Å) |
