PDB: 42091 件ウェブページステータス検索Chemie searchBIRD

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7R4H	phospho-STING binding to adaptor protein complex-1 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Xu, P, Ablasser, A. 登録日 2022-02-08 公開日 2022-09-14 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.34 Å) 主引用文献 Clathrin-associated AP-1 controls termination of STING signalling. Nature, 610, 2022
6RLU	Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine 分子名称: 5'-O-(N-(L-seryl)-sulfamoyl)cytidine, GLYCEROL, MALONATE ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2019-05-02 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
6F6T	Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum complexed with S-APPA 分子名称: (S)-(1-amino-2phenylallyl)phosphonic acid, Phenylalanine ammonia-lyase 1 著者 Bata, Z, Leveles, I, Vertessy, G.B, Poppe, L. 登録日 2017-12-06 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89995968 Å) 主引用文献 Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes Acs Catalysis, 2021
6S2N	Hen egg-white lysozyme by serial electron diffraction 分子名称: Lysozyme C 著者 Buecker, R, Mehrabi, P, Schulz, E.C, Hogan-Lamarre, P. 登録日 2019-06-21 公開日 2020-04-29 最終更新日 2024-10-23 実験手法 ELECTRON CRYSTALLOGRAPHY (1.8 Å) 主引用文献 Serial protein crystallography in an electron microscope. Nat Commun, 11, 2020
4R5B	Human Carbonic Anhydrase II in Complex with a Carbohydrate-Based Sulfamate 分子名称: (6S)-2,6-anhydro-6-{[(3R)-3-(sulfamoyloxy)pyrrolidin-1-yl]sulfonyl}-D-glucitol, Carbonic anhydrase 2, GLYCEROL, ... 著者 Mahon, B.P, McKenna, R. 登録日 2014-08-20 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates. J.Med.Chem., 57, 2014
5ZLV	DNA polymerase IV - DNA ternary complex with 50mM MgCl2 分子名称: DIPHOSPHATE, DNA polymerase IV, DTN1, ... 著者 Kottur, J, Nair, D.T. 登録日 2018-03-29 公開日 2018-11-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
6XC0	Crystal structure of bacteriophage T4 spackle and lysozyme in monoclinic form 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H. 登録日 2020-06-07 公開日 2020-12-02 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural basis of superinfection exclusion by bacteriophage T4 Spackle. Commun Biol, 3, 2020
6LRV	Marsupenaeus japonicus ferritin mutant(T158H) pH9.0 分子名称: Ferritin 著者 Zhao, G, Tan, X, Zhang, T. 登録日 2020-01-16 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking. Commun Chem, 2020
6LS0	rod-shaped crystal of TmFtn mutant-T4FY stimulited by PLL15 分子名称: FE (III) ION, Ferritin 著者 Zhao, G, Zhang, X. 登録日 2020-01-16 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 rod-shaped crystal of TmFtn mutant-T4FY stimulited by PLL15 To Be Published
8PZ0	Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14. 分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, CHLORIDE ION, ... 著者 Simpson, M.C, Czekster, C.M, Harding, C.J. 登録日 2023-07-26 公開日 2023-11-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry, 62, 2023
8PZM	Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 bound to bestatin inhibitor and manganese 分子名称: 1,2-ETHANEDIOL, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, BICARBONATE ION, ... 著者 Simpson, M.C, Czekster, C.M, Harding, C.J. 登録日 2023-07-27 公開日 2023-11-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry, 62, 2023
7QOE	Structure of a small alarmone hydrolase from Leptospira levettii 分子名称: HDc domain-containing protein, MANGANESE (II) ION 著者 Bisiak, F, Brodersen, D.E, Chrenkova, A. 登録日 2021-12-23 公開日 2022-07-13 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response. J.Biol.Chem., 298, 2022
8PZY	Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 - hexameric assembly with manganese bound 分子名称: 1,2-ETHANEDIOL, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, AMMONIUM ION, ... 著者 Simpson, M.C, Czekster, C.M, Harding, C.J. 登録日 2023-07-27 公開日 2023-11-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry, 62, 2023
9GGM	Cryo-EM structure of KBTBD4 P313PRR mutant-HDAC2 2:2 complex 分子名称: Histone deacetylase 2, Isoform 1 of Kelch repeat and BTB domain-containing protein 4, ZINC ION 著者 Chen, Z, Chi, G, Pike, A.C.W, Montes, B, Bullock, A.N. 登録日 2024-08-13 公開日 2025-04-09 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment. Nat Commun, 16, 2025
7QOC	Se-Met derivative structure of a small alarmone hydrolase (RelH) from Corynebacterium glutamicum 分子名称: Guanosine polyphosphate pyrophosphohydrolases/synthetases, MAGNESIUM ION 著者 Bisiak, F, Brodersen, D.E, Chrenkova, A. 登録日 2021-12-23 公開日 2022-07-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response. J.Biol.Chem., 298, 2022
6LLC	Discovery of A Dual Inhibitor of NQO1 and GSTP1 for Treating Malignant Glioblastoma 分子名称: 5-methyl-N-(5-nitro-1,3-thiazol-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1, ... 著者 Ye, K, Li, H. 登録日 2019-12-23 公開日 2020-11-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. J Hematol Oncol, 13, 2020
7RAZ	Small conductance mechanosensitive channel MscS 分子名称: PHOSPHATIDYLETHANOLAMINE, Small-conductance mechanosensitive channel 著者 Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y. 登録日 2021-07-05 公開日 2022-07-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Small conductance mechanosensitive channel MscS To Be Published
6LUR	Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder 分子名称: 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one, Thioredoxin 1,Poly(U)-binding-splicing factor PUF60 著者 Takahashi, M, Hanzawa, H. 登録日 2020-01-30 公開日 2020-04-29 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery. J.Biomol.Nmr, 74, 2020
6LV3	Co- Carbonic Anhydrase II pH 11.0 0 atm CO2 分子名称: COBALT (II) ION, Carbonic anhydrase 2, GLYCEROL 著者 Kim, C.U, Kim, J.K. 登録日 2020-02-02 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Elucidating the role of metal ions in carbonic anhydrase catalysis. Nat Commun, 11, 2020
8EHX	cryo-EM structure of TMEM63B in LMNG 分子名称: CSC1-like protein 2 著者 Zheng, W, Fu, T.M, Holt, J.R. 登録日 2022-09-14 公開日 2023-08-23 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels. Neuron, 111, 2023
4RB2	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Fur-Mn2+-feoAB1 operator 分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
6LV7	Ni- Carbonic Anhydrase II pH 11.0 0 atm CO2 分子名称: Carbonic anhydrase 2, GLYCEROL, NICKEL (II) ION 著者 Kim, C.U, Kim, J.K. 登録日 2020-02-02 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Elucidating the role of metal ions in carbonic anhydrase catalysis. Nat Commun, 11, 2020
5BYI	Human carbonic anhydrase II with an azobenzene inhibitor (1d) 分子名称: 4-(HYDROXYMERCURY)BENZOIC ACID, 4-[(E)-(4-aminophenyl)diazenyl]benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Groll, M, Broichhagen, J. 登録日 2015-06-10 公開日 2015-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Azobenzene-based inhibitors of human carbonic anhydrase II. Beilstein J Org Chem, 11, 2015
8DTY	Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Murayama, T, Samso, M. 登録日 2022-07-26 公開日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions To Be Published
9EGE	BSEP Apo Structure in GDN 分子名称: Bile salt export pump 著者 Reddy, B.G, Gruget, C, Moore, J. 登録日 2024-11-21 公開日 2025-04-02 最終更新日 2025-06-11 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease. Commun Biol, 8, 2025

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