5BYI

Human carbonic anhydrase II with an azobenzene inhibitor (1d)

Summary for 5BYI

• Entry DOI: 10.2210/pdb5byi/pdb
• Related: 2VVA
• Descriptor: Carbonic anhydrase 2, ZINC ION, 4-(HYDROXYMERCURY)BENZOIC ACID, ... (6 entities in total)
• Functional Keywords: carbonic anhydrase, sulfonamide, photopharmacology, inhibitor, lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 30047.69

Authors

Groll, M.,Broichhagen, J. (deposition date: 2015-06-10, release date: 2015-08-05)

• Primary citation: Runtsch, L.S.,Barber, D.M.,Mayer, P.,Groll, M.,Trauner, D.,Broichhagen, J.; Azobenzene-based inhibitors of human carbonic anhydrase II.; Beilstein J Org Chem, 11:1129-1135, 2015; PubMed: 26199669; DOI: 10.3762/bjoc.11.127

Experimental method

X-RAY DIFFRACTION (1.15 Å)