6LUR
Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder
Summary for 6LUR
Entry DOI | 10.2210/pdb6lur/pdb |
Descriptor | Thioredoxin 1,Poly(U)-binding-splicing factor PUF60, 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one (3 entities in total) |
Functional Keywords | splicing factor, splicing |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 8 |
Total formula weight | 199626.26 |
Authors | Takahashi, M.,Hanzawa, H. (deposition date: 2020-01-30, release date: 2020-04-29, Last modification date: 2023-11-29) |
Primary citation | Hanzawa, H.,Shimada, T.,Takahashi, M.,Takahashi, H. Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery. J.Biomol.Nmr, 74:501-508, 2020 Cited by PubMed: 32306215DOI: 10.1007/s10858-020-00314-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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