6LUR
Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Thioredoxin 1,Poly(U)-binding-splicing factor PUF60 | polymer | 222 | 24671.9 | 8 | UniProt (P0AA25) UniProt (Q9UHX1) Pfam (PF00085) In PDB | Escherichia coli (strain K12) | Trx-1,60 kDa poly(U)-binding-splicing factor,FUSE-binding protein-interacting repressor,FBP-interacting repressor,Ro-binding protein 1,RoBP1,Siah-binding protein 1,Siah-BP1 |
2 | B, C, D, E | 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one | non-polymer | 281.4 | 8 | Chemie (EVU) | |||
3 | water | water | 18.0 | 696 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 344 - 452 (UniProt: P0AA25)
A, B, C, D, E, F, G, H: 457 - 556 (UniProt: Q9UHX1)
PDB | External Database | Details |
---|---|---|
Met 335 | - | initiating methionine |
Lys 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
His 342 | - | expression tag |
Pro 343 | - | expression tag |
Gly 453 | - | linker |
Ser 454 | - | linker |
Ala 455 | - | linker |
Met 456 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 197375.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2250.8 | |
All* | Total formula weight | 199626.3 |