8PZM

Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 bound to bestatin inhibitor and manganese

Summary for 8PZM

• Entry DOI: 10.2210/pdb8pzm/pdb
• Related: 8PZO
• Descriptor: Probable cytosol aminopeptidase, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: aminopeptidase, metalloenzyme, hexamer, hydrolase, bestatin, inhibitor, manganese
• Biological source: Pseudomonas aeruginosa PA14
• Total number of polymer chains: 1
• Total formula weight: 55660.64

Authors

Simpson, M.C.,Czekster, C.M.,Harding, C.J. (deposition date: 2023-07-27, release date: 2023-11-15, Last modification date: 2023-12-06)

• Primary citation: Simpson, M.C.,Harding, C.J.,Czekster, R.M.,Remmel, L.,Bode, B.E.,Czekster, C.M.; Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.; Biochemistry, 62:3188-3205, 2023; PubMed: 37924287; DOI: 10.1021/acs.biochem.3c00420

Experimental method

X-RAY DIFFRACTION (1.7 Å)