7S5F
 
 | | Crystal structure of mannose-6-phosphate reductase from celery (Apium graveolens) leaves with NADP+ and mannonic acid bound | | 分子名称: | D-MANNONIC ACID, Manose-6-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, Y, Bhayani, J.A, Romina, I.M, Hartman, M.D, Cereijo, A.E, Ballicora, M.A, Iglesias, A.A, Figueroa, C.M, Liu, D. | | 登録日 | 2021-09-10 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural Determinants of Sugar Alcohol Biosynthesis in Plants: The Crystal Structures of Mannose-6-Phosphate and Aldose-6-Phosphate Reductases.
Plant Cell.Physiol., 63, 2022
|
|
5IJB
 | | The ligand-free structure of the mouse TLR4/MD-2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6YLD
 | | Crystal structure of Trichoplax adhaerens trBcl-2L2 bound to trBak BH3 | | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1, ... | | 著者 | D Sa, J, Banjara, S, Kvansakul, M. | | 登録日 | 2020-04-07 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis.
Sci Adv, 6, 2020
|
|
7AGO
 | | crystal structure of the N-acetylmuramyl-L-alanine amidase, Ami1, from Mycobacterium abscessus bound to L-Alanine-D-isoglutamine | | 分子名称: | ALANINE, D-alpha-glutamine, N-acetylmuramoyl-L-alanine amidase, ... | | 著者 | Blaise, M. | | 登録日 | 2020-09-23 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Functional Characterization of the N -Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus .
Cells, 9, 2020
|
|
6H0P
 | |
7RC6
 | | Aeronamide N-methyltransferase, AerE, bound to modified peptide substrate, AerA-DL,34 | | 分子名称: | Aeronamide A peptide, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Cogan, D.P, Reyes, R, Nair, S.K. | | 登録日 | 2021-07-07 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7S1M
 | |
8SP7
 | |
4YTU
 | | Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with L-erythrulose | | 分子名称: | D-tagatose 3-epimerase, L-Erythrulose, MANGANESE (II) ION | | 著者 | Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. | | 登録日 | 2015-03-18 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates
Appl. Microbiol. Biotechnol., 100, 2016
|
|
8VDY
 | | Crystal Structure of Delta 114-117 D-Dopachrome Tautomerase (D-DT) | | 分子名称: | D-dopachrome decarboxylase | | 著者 | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | 登録日 | 2023-12-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
|
|
8VFL
 | | Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 290K | | 分子名称: | D-dopachrome decarboxylase | | 著者 | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | 登録日 | 2023-12-21 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
|
|
8VFN
 | | Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 310K | | 分子名称: | D-dopachrome decarboxylase | | 著者 | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | 登録日 | 2023-12-21 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
|
|
4UBD
 | | Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | 著者 | Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J. | | 登録日 | 2014-08-12 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
|
|
4XSL
 | | Crystal strcutre of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with glycerol | | 分子名称: | D-tagatose 3-epimerase, GLYCEROL, MANGANESE (II) ION | | 著者 | Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. | | 登録日 | 2015-01-22 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates
Appl. Microbiol. Biotechnol., 100, 2016
|
|
5NH6
 | |
8VG7
 | | Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) | | 分子名称: | D-dopachrome decarboxylase | | 著者 | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | 登録日 | 2023-12-23 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
|
|
5NHA
 | |
8DEJ
 | | D. vulgaris type I-C Cascade bound to dsDNA target | | 分子名称: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | 登録日 | 2022-06-20 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
|
|
5TE3
 | | Crystal structure of Bos taurus opsin at 2.7 Angstrom | | 分子名称: | PALMITIC ACID, Rhodopsin, SULFATE ION, ... | | 著者 | Gulati, S, Kiser, P.D, Palczewski, K. | | 登録日 | 2016-09-20 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5EI5
 | | Crystal structure of MSF-aged Torpedo californica Acetylcholinesterase in complex with alkylene-linked bis-tacrine dimer (7 carbon linker) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | | 著者 | Pesaresi, A, Lamba, D. | | 登録日 | 2015-10-29 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.
Protein Sci., 33, 2024
|
|
4PJ6
 | | Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSINE, ... | | 著者 | Hermans, S.J, Ascher, D.B, Hancock, N.C, Holien, J.K, Michell, B, Morton, C.J, Parker, M.W. | | 登録日 | 2014-05-12 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.
Protein Sci., 24, 2015
|
|
5D8D
 | |
5EHX
 | | Crystal structure of MSF-aged Torpedo californica Acetylcholinesterase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, ... | | 著者 | Pesaresi, A, Lamba, D. | | 登録日 | 2015-10-29 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.
Protein Sci., 33, 2024
|
|
4TVK
 | | TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A CHLOROTACRINE-JUGLONE HYBRID INHIBITOR | | 分子名称: | 2-({2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}amino)-5-hydroxynaphthalene-1,4-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pesaresi, A, Samez, S, Lamba, D. | | 登録日 | 2014-06-27 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects.
J.Med.Chem., 57, 2014
|
|
5DMX
 | |
