6H0P

The structure of C100A mutant of Arabidopsis thaliana UDP-apiose/UDP-xylose synthase in complex with NADH and UDP-D-glucuronic acid

Summary for 6H0P

Entry DOI	10.2210/pdb6h0p/pdb
Descriptor	UDP-D-apiose/UDP-D-xylose synthase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID (3 entities in total)
Functional Keywords	enzyme catalysis, glycobiology, short-chain dehydrogenases/reductases (sdr), aldol cleavage, substrate-assisted reaction, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	2
Total formula weight	89800.79
Authors	Savino, S.,Mattevi, A. (deposition date: 2018-07-10, release date: 2019-10-23, Last modification date: 2024-01-17)
Primary citation	Savino, S.,Borg, A.J.E.,Dennig, A.,Pfeiffer, M.,de Giorgi, F.,Weber, H.,Dubey, K.D.,Rovira, C.,Mattevi, A.,Nidetzky, B. Deciphering the enzymatic mechanism of sugar ring contraction in UDP-apiose biosynthesis. Nat Catal, 2:1115-1123, 2019 Cited by PubMed: 31844840 DOI: 10.1038/s41929-019-0382-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.47 Å)

Structure validation