6H0P
The structure of C100A mutant of Arabidopsis thaliana UDP-apiose/UDP-xylose synthase in complex with NADH and UDP-D-glucuronic acid
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0005777 | cellular_component | peroxisome |
A | 0005829 | cellular_component | cytosol |
A | 0009226 | biological_process | nucleotide-sugar biosynthetic process |
A | 0010396 | biological_process | rhamnogalacturonan II metabolic process |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0033320 | biological_process | UDP-D-xylose biosynthetic process |
A | 0033352 | biological_process | UDP-D-apiose biosynthetic process |
A | 0042802 | molecular_function | identical protein binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0046982 | molecular_function | protein heterodimerization activity |
A | 0048040 | molecular_function | UDP-glucuronate decarboxylase activity |
A | 0051287 | molecular_function | NAD binding |
A | 0071555 | biological_process | cell wall organization |
A | 0102765 | molecular_function | UDP-D-apiose synthase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005777 | cellular_component | peroxisome |
B | 0005829 | cellular_component | cytosol |
B | 0009226 | biological_process | nucleotide-sugar biosynthetic process |
B | 0010396 | biological_process | rhamnogalacturonan II metabolic process |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0033320 | biological_process | UDP-D-xylose biosynthetic process |
B | 0033352 | biological_process | UDP-D-apiose biosynthetic process |
B | 0042802 | molecular_function | identical protein binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0046982 | molecular_function | protein heterodimerization activity |
B | 0048040 | molecular_function | UDP-glucuronate decarboxylase activity |
B | 0051287 | molecular_function | NAD binding |
B | 0071555 | biological_process | cell wall organization |
B | 0102765 | molecular_function | UDP-D-apiose synthase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue NAD A 401 |
Chain | Residue |
A | GLY24 |
A | ALA97 |
A | ALA98 |
A | ALA100 |
A | PHE137 |
A | SER138 |
A | TYR185 |
A | LYS189 |
A | ARG235 |
A | GLY27 |
A | PHE28 |
A | ILE29 |
A | ASP49 |
A | ILE75 |
A | ASN76 |
A | ILE77 |
A | LEU96 |
site_id | AC2 |
Number of Residues | 24 |
Details | binding site for residue UGA A 402 |
Chain | Residue |
A | ALA100 |
A | PRO102 |
A | TYR105 |
A | THR139 |
A | GLU141 |
A | ARG182 |
A | TYR185 |
A | PRO212 |
A | PHE213 |
A | ASN214 |
A | ARG235 |
A | VAL236 |
A | CYS239 |
A | PHE240 |
A | LYS251 |
A | VAL253 |
A | SER258 |
A | ARG260 |
A | VAL298 |
A | PHE330 |
A | TYR331 |
A | TYR335 |
A | ASP337 |
A | ARG341 |
site_id | AC3 |
Number of Residues | 17 |
Details | binding site for residue NAD B 401 |
Chain | Residue |
B | GLY24 |
B | GLY27 |
B | PHE28 |
B | ILE29 |
B | ASP49 |
B | ILE75 |
B | ASN76 |
B | ILE77 |
B | LEU96 |
B | ALA97 |
B | ALA98 |
B | PHE137 |
B | SER138 |
B | TYR185 |
B | LYS189 |
B | PRO212 |
B | ARG235 |
site_id | AC4 |
Number of Residues | 23 |
Details | binding site for residue UGA B 402 |
Chain | Residue |
B | PRO102 |
B | TYR105 |
B | THR139 |
B | GLU141 |
B | ARG182 |
B | TYR185 |
B | PRO212 |
B | PHE213 |
B | ASN214 |
B | ARG235 |
B | VAL236 |
B | CYS239 |
B | LYS251 |
B | LEU252 |
B | VAL253 |
B | SER258 |
B | ARG260 |
B | VAL298 |
B | PHE330 |
B | TYR331 |
B | TYR335 |
B | ASP337 |
B | ARG341 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000250 |
Chain | Residue | Details |
A | TYR185 | |
B | TYR185 |
site_id | SWS_FT_FI2 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP49 | |
B | ARG182 | |
B | TYR185 | |
B | ASN214 | |
B | ARG235 | |
B | VAL236 | |
B | VAL253 | |
B | ASP337 | |
A | ARG182 | |
A | TYR185 | |
A | ASN214 | |
A | ARG235 | |
A | VAL236 | |
A | VAL253 | |
A | ASP337 | |
B | ASP49 |