4PJ6

Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site

Summary for 4PJ6

Entry DOI	10.2210/pdb4pj6/pdb
Descriptor	Leucyl-cystinyl aminopeptidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywords	aminopeptidase, metalloprotease, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	204621.70
Authors	Hermans, S.J.,Ascher, D.B.,Hancock, N.C.,Holien, J.K.,Michell, B.,Morton, C.J.,Parker, M.W. (deposition date: 2014-05-12, release date: 2014-12-03, Last modification date: 2023-12-27)
Primary citation	Hermans, S.J.,Ascher, D.B.,Hancock, N.C.,Holien, J.K.,Michell, B.J.,Yeen Chai, S.,Morton, C.J.,Parker, M.W. Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Sci., 24:190-199, 2015 Cited by PubMed: 25408552 DOI: 10.1002/pro.2604 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.96 Å)

Structure validation