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5DCN
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Crystal structure of LC3 in complex with TECPR2 LIR
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Stadel, D, Huber, J, Dotsch, V, Rogov, V.V, Behrends, C, Akutsu, M.
登録日2015-08-24
公開日2016-03-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.
Mol.Cell, 60, 2015
7MI4
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BU of 7mi4 by Molmil
Symmetrical PAM-PAM prespacer bound Cas4/Cas1/Cas2 complex
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (35-MER), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MI5
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BU of 7mi5 by Molmil
Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (26-MER), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MIB
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BU of 7mib by Molmil
Half integration complex of Cas4/Cas1/Cas2 with Cas4 still on the Non-PAM side
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (31-MER), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MID
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BU of 7mid by Molmil
Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MI9
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BU of 7mi9 by Molmil
Full integration complex of Cas1/Cas2 from Cas4-containing system
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
4S11
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BU of 4s11 by Molmil
Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
分子名称: GELSOLIN NANOBODY
著者Wongsantichon, J, Loonchanta, A, Robinson, R.C, Gettemans, J.
登録日2015-01-07
公開日2015-06-03
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Hum.Mol.Genet., 24, 2015
2H9U
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BU of 2h9u by Molmil
Crystal structure of the archaea specific DNA binding protein
分子名称: 1,2-ETHANEDIOL, DNA/RNA-binding protein Alba 2
著者Kumarevel, T.S, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-06-12
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the archaea specific DNA binding protein from Aeropyrum pernix K1
To be Published
4S10
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Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
分子名称: CALCIUM ION, GELSOLIN NANOBODY, Gelsolin
著者Wongsantichon, J, Robinson, R.C, Gettemans, J.
登録日2015-01-07
公開日2015-06-03
実験手法X-RAY DIFFRACTION (2.614 Å)
主引用文献An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Hum.Mol.Genet., 24, 2015
5BKI
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BU of 5bki by Molmil
Blocker-free closed MthK channel in nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CADMIUM ION, Calcium-gated potassium channel MthK, ...
著者Fan, C, Nimigean, C.M.
登録日2021-03-19
公開日2022-09-21
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Nat.Chem.Biol., 2023
5BKJ
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BU of 5bkj by Molmil
TPeA-bound closed MthK channel in nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, Calcium-gated potassium channel MthK, ...
著者Fan, C, Nimigean, C.M.
登録日2021-03-19
公開日2022-09-21
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Nat.Chem.Biol., 2023
5BKK
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bbTBA-bound closed MthK channel in nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (~{R})-phenyl-[4-[(tributyl-$l^{4}-azanyl)methyl]phenyl]methanol, Calcium-gated potassium channel MthK, ...
著者Fan, C, Nimigean, C.M.
登録日2021-03-19
公開日2022-09-21
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Nat.Chem.Biol., 2023
2LCQ
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BU of 2lcq by Molmil
Solution structure of the endonuclease Nob1 from P.horikoshii
分子名称: Putative toxin VapC6, ZINC ION
著者Veith, T, Martin, R, Wurm, J.P, Weis, B, Duchardt-Ferner, E, Safferthal, C, Hennig, R, Mirus, O, Bohnsack, M.T, Woehnert, J, Schleiff, E.
登録日2011-05-05
公開日2011-12-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of the archaeal endonuclease Nob1.
Nucleic Acids Res., 40, 2012
1M7V
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BU of 1m7v by Molmil
STRUCTURE OF A NITRIC OXIDE SYNTHASE HEME PROTEIN FROM BACILLUS SUBTILIS WITH TETRAHYDROFOLATE AND ARGININE BOUND
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, ARGININE, Nitric Oxide Synthase, ...
著者Pant, K, Bilwes, A.M, Adak, S, Stuehr, D.J, Crane, B.R.
登録日2002-07-22
公開日2002-10-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a nitric oxide synthase heme protein from Bacillus subtilis.
Biochemistry, 41, 2002
1M7Z
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BU of 1m7z by Molmil
Structure of Nitric Oxide Synthase Heme Protein from Bacillus Subtilis with N-Hydroxy-Arginine and Tetrahydrofolate Bound
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, N-OMEGA-HYDROXY-L-ARGININE, Nitric oxide synthase, ...
著者Pant, K, Bilwes, A.M, Adak, S, Stuehr, D.J, Crane, B.R.
登録日2002-07-23
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure of a nitric oxide synthase heme protein from Bacillus subtilis.
Biochemistry, 41, 2002
2Z5E
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BU of 2z5e by Molmil
Crystal Structure of Proteasome Assembling Chaperone 3
分子名称: Proteasome Assembling Chaperone 3
著者Okamoto, K, Kurimoto, E, Sakata, E, Suzuki, A, Yamane, T, Hirano, Y, Murata, S, Tanaka, K, Kato, K.
登録日2007-07-06
公開日2008-02-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
3N2V
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Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide
分子名称: CALCIUM ION, Macrophage metalloelastase, N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide, ...
著者Calderone, V.
登録日2010-05-19
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs).
Eur.J.Med.Chem., 45, 2010
2Z5B
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BU of 2z5b by Molmil
Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly
分子名称: Protein YPL144W, Uncharacterized protein YLR021W
著者Yashiroda, H, Mizushima, T, Okamoto, K, Kameyama, T, Hayashi, H, Kishimoto, T, Kasahara, M, Kurimoto, E, Sakata, E, Suzuki, A, Hirano, Y, Murata, S, Kato, K, Yamane, T, Tanaka, K.
登録日2007-07-03
公開日2008-01-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
3N2U
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BU of 3n2u by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(4-methoxy-N(2-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)ethyl)phenylsulfonamido)acetamide
分子名称: CALCIUM ION, Macrophage metalloelastase, N-hydroxy-2-{[(4-methoxyphenyl)sulfonyl](2-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}ethyl)amino}acetamide, ...
著者Calderone, V.
登録日2010-05-19
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs).
Eur.J.Med.Chem., 45, 2010
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTE
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BU of 2xte by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTC
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BU of 2xtc by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
1VZ0
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BU of 1vz0 by Molmil
Chromosome segregation protein Spo0J from Thermus thermophilus
分子名称: COBALT (II) ION, Chromosome-partitioning protein Spo0J, MAGNESIUM ION
著者Leonard, T.A, Butler, P.J.G, Lowe, J.
登録日2004-05-12
公開日2004-07-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of the chromosome segregation protein Spo0J from Thermus thermophilus.
Mol. Microbiol., 53, 2004
8FZ7
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BU of 8fz7 by Molmil
TpeA bound closed MthK-A88F mutant in nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, Calcium-gated potassium channel MthK, ...
著者Agarwal, S, Nimigean, C.M.
登録日2023-01-27
公開日2023-10-11
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Nat.Chem.Biol., 20, 2024
3W8Q
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Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1)
分子名称: Dual specificity mitogen-activated protein kinase kinase 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Nakae, S, Kitamura, M, Shirai, T, Tada, T.
登録日2013-03-20
公開日2014-03-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of mitogen-activated protein kinase kinase 1 in the DFG-out conformation.
Acta Crystallogr.,Sect.F, 77, 2021

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