8FZ7

TpeA bound closed MthK-A88F mutant in nanodisc

Summary for 8FZ7

Entry DOI	10.2210/pdb8fz7/pdb
EMDB information	27459 29605
Descriptor	Calcium-gated potassium channel MthK, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, ... (4 entities in total)
Functional Keywords	mthk, transport protein, ion channel, blocker tpea, membrane protein
Biological source	Methanothermobacter thermautotrophicus
Total number of polymer chains	8
Total formula weight	302830.86
Authors	Agarwal, S.,Nimigean, C.M. (deposition date: 2023-01-27, release date: 2023-10-11, Last modification date: 2024-01-03)
Primary citation	Fan, C.,Flood, E.,Sukomon, N.,Agarwal, S.,Allen, T.W.,Nimigean, C.M. Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 20:52-61, 2024 Cited by PubMed: 37653172 DOI: 10.1038/s41589-023-01406-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.88 Å)

Structure validation