4S11
Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
Summary for 4S11
Entry DOI | 10.2210/pdb4s11/pdb |
Related | 4S10 |
Descriptor | GELSOLIN NANOBODY (2 entities in total) |
Functional Keywords | nanobody, immune system |
Biological source | Lama glama |
Total number of polymer chains | 1 |
Total formula weight | 14110.42 |
Authors | Wongsantichon, J.,Loonchanta, A.,Robinson, R.C.,Gettemans, J. (deposition date: 2015-01-07, release date: 2015-06-03) |
Primary citation | Van Overbeke, W.,Wongsantichon, J.,Everaert, I.,Verhelle, A.,Zwaenepoel, O.,Loonchanta, A.,Burtnick, L.D.,De Ganck, A.,Hochepied, T.,Haigh, J.,Cuvelier, C.,Derave, W.,Robinson, R.C.,Gettemans, J. An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model. Hum.Mol.Genet., 24:2492-2507, 2015 Cited by PubMed: 25601851DOI: 10.1093/hmg/ddv010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.998 Å) |
Structure validation
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