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6C84
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BU of 6c84 by Molmil
Crystal structure of PBP5 from Enterococcus faecium
分子名称: Penicillin-binding protein
著者Shamoo, Y, Davlieva, M.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.511 Å)
主引用文献Crystal structure of PBP5 from Enterococcus faecium
To Be Published
6NLW
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BU of 6nlw by Molmil
The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
分子名称: Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Tan, K, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-09
公開日2019-01-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
To Be Published
6NHS
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BU of 6nhs by Molmil
Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Kim, Y, Tesar, C, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-23
公開日2019-01-16
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
To Be Published
6NHU
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BU of 6nhu by Molmil
Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, GLYCEROL, ...
著者Kim, Y, Welk, L, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-23
公開日2019-01-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
To Be Published
6N6W
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BU of 6n6w by Molmil
OXA-23 mutant F110A/M221A neutral pH form
分子名称: Beta-lactamase oxa23
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6V
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BU of 6n6v by Molmil
OXA-23 mutant F110A/M221A low pH form meropenem complex
分子名称: Beta-lactamase, meropenem, bound form
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6Y
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BU of 6n6y by Molmil
OXA-23 mutant F110A/M221A neutral pH form meropenem complex
分子名称: Beta-lactamase oxa23, meropenem, bound form
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6X
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BU of 6n6x by Molmil
OXA-23 mutant F110A/M221A neutral pH form imipenem complex
分子名称: Beta-lactamase oxa23, Imipenem, SULFATE ION
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6U
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BU of 6n6u by Molmil
OXA-23 mutant F110A/M221A low pH form imipenem complex
分子名称: Beta-lactamase, Imipenem
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N1N
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BU of 6n1n by Molmil
Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386
分子名称: Beta-lactamase, GLYCEROL, SULFATE ION
著者Michalska, K, Tesar, C, Endres, M, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-09
公開日2018-12-19
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386
To Be Published
6N6T
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BU of 6n6t by Molmil
OXA-23 mutant F110A/M221A low pH form
分子名称: Beta-lactamase oxa23, CITRATE ANION
著者Smith, C.A, Vakulenko, S.B.
登録日2018-11-27
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6MKF
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BU of 6mkf by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the imipenem-bound form
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKH
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BU of 6mkh by Molmil
Crystal structure of pencillin binding protein 4 (PBP4) from Enterococcus faecalis in the imipenem-bound form
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, PHOSPHATE ION, pencillin binding protein 4 (PBP4)
著者D'Andrea, E.D, Moon, T.M, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKA
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BU of 6mka by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the open conformation
分子名称: SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKG
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BU of 6mkg by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the benzylpenicilin-bound form
分子名称: OPEN FORM - PENICILLIN G, SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKI
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BU of 6mki by Molmil
Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the ceftaroline-bound form
分子名称: Ceftaroline, bound form, GLYCEROL, ...
著者D'Andrea, E.D, Moon, T.M, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MKJ
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BU of 6mkj by Molmil
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the closed conformation
分子名称: penicillin binding protein 5 (PBP5)
著者Moon, T.M, Soares, A, D'Andrea, E.D, Jaconcic, J, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.864 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6BSR
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BU of 6bsr by Molmil
Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the benzylpenicillin bound form.
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6BSQ
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BU of 6bsq by Molmil
Enterococcus faecalis Penicillin Binding Protein 4 (PBP4)
分子名称: CHLORIDE ION, GLYCEROL, PBP4 protein
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6B22
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BU of 6b22 by Molmil
Crystal structure OXA-24 beta-lactamase complexed with WCK 4234 by co-crystallization
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carbonitrile, Beta-lactamase, CHLORIDE ION
著者van den Akker, F, Nguyen, N.Q.
登録日2017-09-19
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using beta-Lactamase Inhibitors and beta-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.
J. Med. Chem., 61, 2018
5OFT
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BU of 5oft by Molmil
Structural basis for OXA-48 dimerization
分子名称: Beta-lactamase
著者Lund, B.A, Nesheim, B.H.B, Leiros, H.K.S.
登録日2017-07-11
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
6GOA
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BU of 6goa by Molmil
Structural basis for OXA-48 dimerization - R189A mutant
分子名称: Beta-lactamase, CHLORIDE ION
著者Lund, B.A, Thomassen, A.M, Leiros, H.K.S.
登録日2018-06-01
公開日2018-07-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
5OAU
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BU of 5oau by Molmil
Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae
分子名称: Penicillin-binding protein 2X
著者Bernardo-Garcia, N, Hermoso, J.A.
登録日2017-06-23
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae.
ACS Chem. Biol., 13, 2018
5OJ1
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Penicillin Binding Protein 2x (PBP2x) from S.pneumoniae in complex with Oxacillin and a tetrasaccharide
分子名称: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Penicillin-binding protein 2X, SODIUM ION
著者Bernardo-Garcia, N, Hermoso, J.A.
登録日2017-07-20
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae.
ACS Chem. Biol., 13, 2018
5OIZ
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BU of 5oiz by Molmil
Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with oxacillin
分子名称: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Penicillin-binding protein 2X
著者Bernardo-Garcia, N, Hermoso, J.A.
登録日2017-07-20
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae.
ACS Chem. Biol., 13, 2018

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