6GOA

Structural basis for OXA-48 dimerization - R189A mutant

Summary for 6GOA

• Entry DOI: 10.2210/pdb6goa/pdb
• Descriptor: Beta-lactamase, CHLORIDE ION (3 entities in total)
• Functional Keywords: dimerization, oxa-48, oxacillinase, carbapenemase, beta-lactamase, antibiotic, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 8
• Total formula weight: 225866.72

Authors

Lund, B.A.,Thomassen, A.M.,Leiros, H.K.S. (deposition date: 2018-06-01, release date: 2018-07-18, Last modification date: 2024-01-17)

• Primary citation: Lund, B.A.,Thomassen, A.M.,Nesheim, B.H.B.,Carlsen, T.J.O.,Isaksson, J.,Christopeit, T.,Leiros, H.S.; The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.; FEBS J., 285:4214-4228, 2018; PubMed: 30153368; DOI: 10.1111/febs.14643

Experimental method

X-RAY DIFFRACTION (2.55 Å)