5OFT

Structural basis for OXA-48 dimerization

Summary for 5OFT

• Entry DOI: 10.2210/pdb5oft/pdb
• Related: 5dtk
• Descriptor: Beta-lactamase (2 entities in total)
• Functional Keywords: dimerization, oxa-48, oxacillinase, carbapenemase, beta-lactamase, antibiotic
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 56281.67

Authors

Lund, B.A.,Nesheim, B.H.B.,Leiros, H.K.S. (deposition date: 2017-07-11, release date: 2018-08-01, Last modification date: 2024-01-17)

• Primary citation: Lund, B.A.,Thomassen, A.M.,Nesheim, B.H.B.,Carlsen, T.J.O.,Isaksson, J.,Christopeit, T.,Leiros, H.S.; The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.; FEBS J., 285:4214-4228, 2018; PubMed: 30153368; DOI: 10.1111/febs.14643

Experimental method

X-RAY DIFFRACTION (3.2 Å)